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Catalog Number:
15111
CAS Number:
478183-70-9
Fmoc-2-nitro-D-phenylalanine
Purity:
≥ 98% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-Phe(2-NO2)-OH, Fmoc-o-nitro-D-Phe-OH
Documents
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Product Information

Fmoc-2-nitro-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound, known for its protective Fmoc (fluorenylmethyloxycarbonyl) group, facilitates the efficient assembly of peptides by providing a stable and easily removable protecting group for the amino functionality. The presence of the nitro group enhances its reactivity, making it an excellent choice for researchers focused on developing novel therapeutic peptides. Its unique structure allows for the introduction of specific functionalities, enabling the design of peptides with tailored properties for various applications, including targeted drug delivery and biomolecular research.

In addition to its role in peptide synthesis, Fmoc-2-nitro-D-phenylalanine has shown potential in the development of bioactive compounds and can serve as a building block in the creation of complex molecular architectures. Its compatibility with standard coupling reagents and methodologies makes it a preferred choice among chemists and biochemists. Researchers can leverage this compound to explore new avenues in medicinal chemistry, enhancing the efficacy and specificity of peptide-based therapeutics.

Synonyms
Fmoc-D-Phe(2-NO2)-OH, Fmoc-o-nitro-D-Phe-OH
CAS Number
478183-70-9
Purity
≥ 98% (HPLC, Chiral purity)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD01317714
PubChem ID
53395421
Appearance
Off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(2-NO2)-OH, Fmoc-o-nitro-D-Phe-OH
CAS Number
478183-70-9
Purity
≥ 98% (HPLC, Chiral purity)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD01317714
PubChem ID
53395421
Appearance
Off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-nitro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide chains with specific functionalities.
  • Drug Development: Its unique structure makes it valuable in medicinal chemistry for designing novel pharmaceuticals, especially those targeting specific receptors or enzymes.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules such as proteins and antibodies to enhance drug delivery systems.
  • Research in Neurobiology: It is utilized in studies related to neurotransmitter systems, helping researchers explore the effects of modified amino acids on neuronal signaling.
  • Fluorescent Labeling: Fmoc-2-nitro-D-phenylalanine can be employed in the development of fluorescent probes, aiding in the visualization of biological processes in real-time.

Citations