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Catalog Number:
15119
CAS Number:
210282-30-7
Fmoc-2-nitro-L-phenylalanine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Phe(2-NO2)-OH, Fmoc-o-nitro-L-Phe-OH
Documents
$65.40 /1G
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Product Information

Fmoc-2-nitro-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for complex peptides. Its unique nitro group enhances the compound's reactivity and can facilitate the introduction of various functional groups, providing researchers with a powerful tool for designing novel therapeutic agents.

In addition to its role in peptide synthesis, Fmoc-2-nitro-L-phenylalanine has applications in the development of targeted drug delivery systems and in the study of protein interactions. Its ability to serve as a versatile intermediate allows chemists to explore a range of biological activities, making it invaluable in medicinal chemistry and biochemistry research. The compound's stability and compatibility with various coupling reagents further enhance its utility, ensuring that it meets the rigorous demands of modern research and development.

Synonyms
Fmoc-L-Phe(2-NO2)-OH, Fmoc-o-nitro-L-Phe-OH
CAS Number
210282-30-7
Purity
≥ 97% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD01317717
PubChem ID
53395421
Appearance
Pale yellow to off-white solid
Optical Rotation
[a]D20 = -8 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Phe(2-NO2)-OH, Fmoc-o-nitro-L-Phe-OH
CAS Number
210282-30-7
Purity
≥ 97% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.4
MDL Number
MFCD01317717
PubChem ID
53395421
Appearance
Pale yellow to off-white solid
Optical Rotation
[a]D20 = -8 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-nitro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the introduction of nitro groups that can be further modified.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific biological pathways involving nitroaromatic compounds.
  • Bioconjugation: The nitro group can be used for selective bioconjugation reactions, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies.
  • Research in Chemical Biology: It is employed in studies exploring the interactions between peptides and proteins, helping researchers understand mechanisms of action in biological systems.
  • Fluorescent Probes: The compound can be modified to create fluorescent probes for imaging applications, enhancing the visualization of cellular processes in live cells.

Citations