Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
15170
CAS Number:
203866-20-0
2S,4R-4-Fluoro-1-Fmoc-pyrrolidine-2-carboxylic acid
Purity:
≥ 97% (HPLC, Chiral purity)
Synonym(s):
Fmoc-trans-4-fluoro-L-Pro-OH
Documents
$100.05 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

(2S,4R)-4-Fluoro-1-Fmoc-pyrrolidine-2-carboxylic acid is a versatile compound widely utilized in the field of peptide synthesis and medicinal chemistry. This fluorinated amino acid derivative features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is crucial for the selective protection of amine functionalities during the synthesis of complex peptides. Its unique fluorine substitution enhances the compound's stability and reactivity, making it an excellent choice for researchers aiming to develop novel therapeutic peptides with improved pharmacological properties.

In addition to its role in peptide synthesis, this compound is also valuable in the development of fluorinated pharmaceuticals, where the incorporation of fluorine can significantly influence the biological activity and metabolic stability of drug candidates. Its application extends to various fields, including drug discovery, biochemistry, and molecular biology, where it serves as a building block for the synthesis of bioactive molecules. Researchers can leverage the unique properties of (2S,4R)-4-Fluoro-1-Fmoc-pyrrolidine-2-carboxylic acid to enhance their projects and achieve more efficient results in their studies.

Synonyms
Fmoc-trans-4-fluoro-L-Pro-OH
CAS Number
203866-20-0
Purity
≥ 97% (HPLC, Chiral purity)
Molecular Formula
C20H18FNO4
Molecular Weight
355.37
MDL Number
MFCD03424224
PubChem ID
4712599
Appearance
White to pale yellow solid
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-trans-4-fluoro-L-Pro-OH
CAS Number
203866-20-0
Purity
≥ 97% (HPLC, Chiral purity)
Molecular Formula
C20H18FNO4
Molecular Weight
355.37
MDL Number
MFCD03424224
PubChem ID
4712599
Appearance
White to pale yellow solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4R)-4-Fluoro-1-Fmoc-pyrrolidine-2-carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of the process.
  • Drug Development: Its unique structure allows for the development of novel pharmaceutical compounds, especially in the creation of drugs targeting specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Research in Neuroscience: This compound is valuable in neuroscience research, particularly in the study of neurotransmitter systems, due to its ability to modify biological activity in specific pathways.
  • Fluorine Chemistry: Its fluorinated nature provides unique properties that are beneficial in various chemical reactions, making it a preferred choice for researchers looking to explore fluorine's effects in organic synthesis.

Citations