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Catalog Number:
15256
CAS Number:
220497-68-7
Fmoc-(S-3-amino-3-(4-bromophenyl)propionic acid
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-β-Phe(4-Br)-OH, (S-Fmoc-4-bromo-β-phenylalanine
Documents
$120.88 /250MG
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Product Information

Fmoc-(S)-3-amino-3-(4-bromophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protective group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its structural characteristics, including the presence of a bromophenyl group, enhance its reactivity and compatibility with various coupling reactions, making it an essential tool for researchers in medicinal chemistry and biochemistry.

This compound is particularly beneficial for the synthesis of peptides with specific biological activities, allowing for the exploration of new therapeutic agents. Its application extends to the development of peptide-based drugs, where the precise control of amino acid sequences is critical. Researchers appreciate its stability and ease of use, which streamline the synthesis process while ensuring high yields. With its unique properties, Fmoc-(S)-3-amino-3-(4-bromophenyl)propionic acid stands out as a valuable asset in the toolkit of professionals engaged in peptide research and development.

Synonyms
Fmoc-L-β-Phe(4-Br)-OH, (S-Fmoc-4-bromo-β-phenylalanine
CAS Number
220497-68-7
Purity
≥ 97% (HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.33
MDL Number
MFCD01311760
PubChem ID
2759183
Melting Point
185-190 °C
Appearance
Off-white powder
Optical Rotation
[α]D25 = -32 ± 2° (C=1, DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-Phe(4-Br)-OH, (S-Fmoc-4-bromo-β-phenylalanine
CAS Number
220497-68-7
Purity
≥ 97% (HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.33
MDL Number
MFCD01311760
PubChem ID
2759183
Melting Point
185-190 °C
Appearance
Off-white powder
Optical Rotation
[α]D25 = -32 ± 2° (C=1, DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(4-bromophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its Fmoc protecting group allows for selective deprotection and coupling reactions.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceuticals, especially in developing compounds targeting specific receptors or enzymes related to various diseases.
  • Bioconjugation: The compound can be used to create bioconjugates, linking peptides to other biomolecules, which is essential in developing targeted therapies and diagnostics.
  • Research on Protein Interactions: It aids in studying protein-protein interactions by providing a means to incorporate specific amino acids into proteins, allowing researchers to investigate their functional roles.
  • Material Science: The compound can be utilized in creating functionalized materials, enhancing properties such as conductivity or reactivity, which are crucial in developing advanced materials for electronics or catalysis.

Citations