🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
15453
CAS Number:
479064-98-7
Fmoc-(R)-3-amino-3-(4-methylphenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(4-Me)-OH, (R)-Fmoc-4-methyl-β-phenylalanine
Documents
$50.30 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-(R)-3-amino-3-(4-methylphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound, characterized by its Fmoc (fluorenylmethyloxycarbonyl) protective group, offers enhanced stability and ease of handling during the synthesis of peptides. Its unique structure, featuring a chiral center, allows for the production of enantiomerically pure compounds, which is crucial in pharmaceutical applications where stereochemistry can significantly influence biological activity.

Researchers and industry professionals appreciate its role in the development of bioactive peptides and drug candidates, particularly in the fields of oncology and neurology. The compound's ability to facilitate the introduction of aromatic side chains enhances the pharmacological properties of synthesized peptides, making it an essential tool in drug discovery. With its favorable solubility and compatibility with various coupling reagents, Fmoc-(R)-3-amino-3-(4-methylphenyl)propionic acid stands out as a reliable choice for those seeking efficiency and precision in peptide synthesis.

Synonyms
Fmoc-D-β-Phe(4-Me)-OH, (R)-Fmoc-4-methyl-β-phenylalanine
CAS Number
479064-98-7
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03428011
PubChem ID
2759200
Melting Point
190 - 191 °C
Appearance
White solid
Optical Rotation
[a]D25 = 36 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Phe(4-Me)-OH, (R)-Fmoc-4-methyl-β-phenylalanine
CAS Number
479064-98-7
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03428011
PubChem ID
2759200
Melting Point
190 - 191 °C
Appearance
White solid
Optical Rotation
[a]D25 = 36 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(4-methylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors, due to its ability to modify peptide sequences effectively.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules, which is crucial for creating targeted therapies and diagnostic agents.
  • Research in Neuroscience: Its unique structure allows researchers to explore neuroactive peptides, contributing to the understanding of neurological pathways and potential treatments for neurological disorders.
  • Custom Peptide Libraries: This chemical is essential in creating custom peptide libraries for high-throughput screening, facilitating the discovery of new bioactive compounds and therapeutic leads.

Citations