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Catalog Number:
15540
CAS Number:
500770-71-8
Boc-(S-3-amino-3-(2-fluorophenyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-β-Phe(2-F)-OH, (S-Boc-2-fluoro-β-phenylalanine
Documents
$74.81 /250MG
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Product Information

Boc-(S)-3-amino-3-(2-fluorophenyl)propionic acid is a valuable building block in pharmaceutical and biochemical research, particularly in the development of novel therapeutics. This compound features a unique fluorophenyl group, which enhances its biological activity and selectivity, making it an ideal candidate for the synthesis of peptide-based drugs. Its Boc (tert-butyloxycarbonyl) protecting group allows for easy manipulation during chemical reactions, facilitating the incorporation of this amino acid into larger peptide chains. Researchers have utilized this compound in the design of inhibitors and modulators, particularly in the fields of cancer and neurological disorders, where precision in molecular interaction is crucial.

The compound's specific stereochemistry and functional groups contribute to its potential in creating targeted therapies with improved efficacy and reduced side effects. Its versatility in synthetic applications, combined with its favorable properties, positions Boc-(S)-3-amino-3-(2-fluorophenyl)propionic acid as a key ingredient in the ongoing quest for innovative solutions in drug discovery and development.

Synonyms
Boc-L-β-Phe(2-F)-OH, (S-Boc-2-fluoro-β-phenylalanine
CAS Number
500770-71-8
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18FNO4
Molecular Weight
283.3
MDL Number
MFCD03427917
PubChem ID
2756795
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -34 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-β-Phe(2-F)-OH, (S-Boc-2-fluoro-β-phenylalanine
CAS Number
500770-71-8
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18FNO4
Molecular Weight
283.3
MDL Number
MFCD03427917
PubChem ID
2756795
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -34 ± 2º (C=1 in EtOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-(S)-3-amino-3-(2-fluorophenyl)propionic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific functionalities, enhancing drug design.
  • Bioconjugation: The compound can be employed in bioconjugation processes, facilitating the attachment of drugs to antibodies or other biomolecules, improving targeted therapy.
  • Research in Chemical Biology: It plays a role in chemical biology studies, helping scientists understand protein interactions and enzyme mechanisms, which is crucial for drug discovery.
  • Fluorine Chemistry: The presence of fluorine in its structure allows for unique properties in medicinal chemistry, making it valuable for creating compounds with enhanced metabolic stability.

Citations