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Catalog Number:
15558
CAS Number:
511272-53-0
Fmoc-(R-3-amino-3-(3-chlorophenyl)propionic acid
Synonym(s):
Fmoc-D-β-Phe(3-Cl)-OH, (R-Fmoc-3-chloro-β-phenylalanine
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$206.60 /1G
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Product Information

Fmoc-(R)-3-amino-3-(3-chlorophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its chiral nature, derived from the (R)-configuration, allows for the creation of enantiomerically pure compounds, making it particularly valuable in pharmaceutical research and development.

Researchers appreciate its application in the synthesis of bioactive peptides, which can serve as potential therapeutics in various medical fields, including oncology and neurology. The presence of the 3-chlorophenyl group enhances the compound's ability to interact with biological targets, potentially improving the efficacy of synthesized peptides. With its reliable performance and compatibility with standard peptide coupling reagents, Fmoc-(R)-3-amino-3-(3-chlorophenyl)propionic acid stands out as a crucial reagent for chemists focused on innovative drug design and development.

Synonyms
Fmoc-D-β-Phe(3-Cl)-OH, (R-Fmoc-3-chloro-β-phenylalanine
CAS Number
511272-53-0
Molecular Formula
C24H20ClNO4
Molecular Weight
421.88
MDL Number
MFCD03428035
PubChem ID
22831638
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(3-Cl)-OH, (R-Fmoc-3-chloro-β-phenylalanine
CAS Number
511272-53-0
Molecular Formula
C24H20ClNO4
Molecular Weight
421.88
MDL Number
MFCD03428035
PubChem ID
22831638
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3-chlorophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), where it helps in the formation of complex peptide chains.
  • Drug Development: Its unique structure allows for the design of novel pharmaceutical compounds, making it valuable in the development of targeted therapies for various diseases.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.
  • Research in Neuroscience: It plays a role in studying neuroactive peptides, which can lead to insights into neurological disorders and potential treatments.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to specific research needs, thus providing flexibility for researchers in academia and industry.

Citations