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Catalog Number:
15563
CAS Number:
517905-84-9
Fmoc-(R-3-amino-3-(2-bromophenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(2-Br)-OH, (R-Fmoc-2-bromo-β-phenylalanine
Documents
$65.40 /250MG
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Product Information

Fmoc-(R)-3-amino-3-(2-bromophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protective group, which facilitates the selective protection of amino groups during the synthesis of peptides. Its specific structure, characterized by the presence of a bromophenyl moiety, enhances its reactivity and allows for the introduction of diverse functionalities, making it an invaluable tool for researchers in drug development and biochemical studies.

In practical applications, Fmoc-(R)-3-amino-3-(2-bromophenyl)propionic acid is particularly beneficial in the design of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its ability to undergo various coupling reactions enables the creation of complex peptide libraries, which are essential for screening potential drug candidates. Additionally, its stability under standard reaction conditions ensures reliable performance in laboratory settings, making it a preferred choice for both academic and industrial chemists focused on innovative drug discovery.

Synonyms
Fmoc-D-β-Phe(2-Br)-OH, (R-Fmoc-2-bromo-β-phenylalanine
CAS Number
517905-84-9
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.33
MDL Number
MFCD03428037
PubChem ID
22831636
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(2-Br)-OH, (R-Fmoc-2-bromo-β-phenylalanine
CAS Number
517905-84-9
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20BrNO4
Molecular Weight
466.33
MDL Number
MFCD03428037
PubChem ID
22831636
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(2-bromophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound is commonly used as a building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences for various applications in biochemistry and pharmacology.
  • Drug Development: Its unique structure makes it valuable in the development of new pharmaceuticals, particularly in designing compounds that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The chemical can be employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Research in Neuroscience: Due to its ability to mimic neurotransmitters, it is used in neuroscience research to study receptor interactions and the effects of various compounds on neural pathways.
  • Analytical Chemistry: This compound serves as a standard in analytical methods, aiding in the quantification and characterization of similar compounds in complex mixtures, thus improving the accuracy of research findings.

Citations