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Catalog Number:
15587
CAS Number:
517905-88-3
Fmoc-(R-3-amino-3-(4-trifluoromethylphenyl)propionic acid
Synonym(s):
Fmoc-D-β-Phe(4-CF3)-OH, (R-Fmoc-4-trifluoromethyl-β-phenylalanine
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$206.60 /1G
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Product Information

Fmoc-(R)-3-amino-3-(4-trifluoromethylphenyl)propionic acid is a specialized amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a unique trifluoromethyl group, which enhances its biological activity and stability, making it an excellent choice for researchers focused on developing novel therapeutic peptides. Its Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains, facilitating streamlined synthesis processes.

In addition to its role in peptide synthesis, this compound has shown potential in the development of targeted drug delivery systems and in the study of structure-activity relationships in medicinal chemistry. Its distinctive properties enable researchers to explore new avenues in drug design, particularly in the creation of compounds with improved efficacy and reduced side effects. With its robust applications in both academic and industrial settings, Fmoc-(R)-3-amino-3-(4-trifluoromethylphenyl)propionic acid stands out as a valuable tool for advancing peptide-based therapeutics.

Synonyms
Fmoc-D-β-Phe(4-CF3)-OH, (R-Fmoc-4-trifluoromethyl-β-phenylalanine
CAS Number
517905-88-3
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428041
PubChem ID
2759206
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(4-CF3)-OH, (R-Fmoc-4-trifluoromethyl-β-phenylalanine
CAS Number
517905-88-3
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428041
PubChem ID
2759206
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(4-trifluoromethylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an important building block in solid-phase peptide synthesis, allowing for the creation of complex peptides with specific functionalities.
  • Drug Development: Its unique structure makes it valuable in medicinal chemistry, particularly in the design of novel pharmaceuticals targeting specific biological pathways.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of peptides to other biomolecules, which is crucial for developing targeted therapies.
  • Research in Neuroscience: Due to its ability to modulate receptor activity, it is explored in studies related to neurological disorders, helping researchers understand drug interactions at a molecular level.
  • Fluorinated Compound Applications: The trifluoromethyl group enhances the compound's metabolic stability, making it an attractive candidate in the development of fluorinated drugs that require prolonged activity in biological systems.

Citations