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Catalog Number:
15660
CAS Number:
511272-36-9
Fmoc-(R)-3-amino-3-(4-hydroxyphenyl)propionic acid
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-β-Phe(4-OH)-OH, Fmoc-D-β-Tyr-OH
Documents
$75.00 /250MG
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Product Information

Fmoc-(R)-3-amino-3-(4-hydroxyphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its unique structure, characterized by the presence of a 4-hydroxyphenyl group, enhances its reactivity and compatibility with various coupling agents, making it an ideal choice for researchers focused on developing complex peptides and bioactive compounds.

In addition to its role in peptide synthesis, Fmoc-(R)-3-amino-3-(4-hydroxyphenyl)propionic acid has potential applications in drug discovery and development, particularly in the design of inhibitors and modulators for therapeutic targets. Its ability to facilitate the introduction of functional groups allows for the creation of diverse molecular libraries, which can be screened for biological activity. This compound stands out for its stability and ease of use, providing researchers with a reliable tool for advancing their projects in pharmaceutical and biochemical research.

Synonyms
Fmoc-D-β-Phe(4-OH)-OH, Fmoc-D-β-Tyr-OH
CAS Number
511272-36-9
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H21NO5
Molecular Weight
403.43
MDL Number
MFCD03428017
PubChem ID
24902256
Appearance
Light yellow powder
Optical Rotation
[a]D20 = 40 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Phe(4-OH)-OH, Fmoc-D-β-Tyr-OH
CAS Number
511272-36-9
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H21NO5
Molecular Weight
403.43
MDL Number
MFCD03428017
PubChem ID
24902256
Appearance
Light yellow powder
Optical Rotation
[a]D20 = 40 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(4-hydroxyphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its structure is beneficial in the design of novel pharmaceuticals, particularly in developing compounds that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The Fmoc protecting group enables selective reactions in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other compounds for drug delivery systems.
  • Research in Neuroscience: This amino acid derivative is used in studies related to neurotransmitter function and receptor interactions, contributing to the understanding of neurological disorders.
  • Material Science: It finds applications in the development of functionalized polymers and materials, enhancing properties such as biocompatibility and mechanical strength for various industrial applications.

Citations