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Catalog Number:
15684
CAS Number:
511272-40-5
Fmoc-(R-3-amino-3-(3,4-dimethoxyphenyl)propionic acid
Synonym(s):
Fmoc-D-β-Phe(3,4-dimethoxy)-OH, (R-Fmoc-3,4-dimethoxy-β-phenylalanine
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Product Information

Fmoc-(R)-3-amino-3-(3,4-dimethoxyphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 3,4-dimethoxyphenyl group, enhances its reactivity and solubility, making it an excellent choice for researchers focusing on complex peptide sequences.

In the pharmaceutical industry, this compound serves as a crucial intermediate in the development of bioactive peptides, which have applications in therapeutic areas such as oncology and immunology. Its ability to facilitate the synthesis of modified peptides allows for the exploration of novel drug candidates with improved efficacy and reduced side effects. Researchers appreciate its stability and compatibility with various coupling reagents, which streamline the synthesis process and enhance overall yield.

Synonyms
Fmoc-D-β-Phe(3,4-dimethoxy)-OH, (R-Fmoc-3,4-dimethoxy-β-phenylalanine
CAS Number
511272-40-5
Molecular Formula
C26H25NO6
Molecular Weight
447.49
MDL Number
MFCD03428021
PubChem ID
22309350
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(3,4-dimethoxy)-OH, (R-Fmoc-3,4-dimethoxy-β-phenylalanine
CAS Number
511272-40-5
Molecular Formula
C26H25NO6
Molecular Weight
447.49
MDL Number
MFCD03428021
PubChem ID
22309350
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3,4-dimethoxyphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, facilitating the assembly of complex peptide sequences.
  • Drug Development: In pharmaceutical research, it is employed to develop peptide-based drugs. Its unique structure can enhance the bioactivity and stability of therapeutic peptides, making it valuable in designing new medications.
  • Bioconjugation: The compound can be used in bioconjugation techniques, where it helps to attach peptides to other biomolecules, such as antibodies or drugs, improving their targeting and efficacy in treatments.
  • Research in Neuroscience: Its structural properties make it useful in studying neuropeptides, which play critical roles in brain function and behavior. Researchers can utilize it to explore new pathways for neurological therapies.
  • Material Science: The compound can also find applications in creating functionalized materials, such as hydrogels or nanomaterials, which can be used in drug delivery systems or tissue engineering, enhancing the performance of biomaterials.

Citations