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Catalog Number:
16637
CAS Number:
101555-60-6
Boc-D-β-homoproline
Purity:
≥ 96%
Synonym(s):
Boc-D-β-HomoPro-OH, (R-2-Carboxymethyl-pyrrolidine-1-carboxylic acidtert-butyl ester
Documents
$93.14 /250MG
Pack Size Availability Price
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Product Information

Boc-D-b-homoproline is a valuable building block in peptide synthesis and medicinal chemistry, recognized for its unique structural features that enhance the stability and bioactivity of peptides. This compound, with its tert-butoxycarbonyl (Boc) protecting group, facilitates the selective functionalization of amino acids, making it an essential tool for researchers engaged in the development of pharmaceuticals and biologically active compounds. Its ability to mimic natural amino acids while providing increased steric hindrance allows for the creation of more complex and effective peptide structures.

In practical applications, Boc-D-b-homoproline is widely utilized in the synthesis of cyclic peptides and peptidomimetics, which are crucial in drug discovery and development. Its incorporation into peptide sequences can lead to improved binding affinity and specificity for biological targets, making it a preferred choice for researchers aiming to enhance therapeutic efficacy. Additionally, its compatibility with various coupling reagents and methods streamlines the synthesis process, saving time and resources in laboratory settings.

Synonyms
Boc-D-β-HomoPro-OH, (R-2-Carboxymethyl-pyrrolidine-1-carboxylic acidtert-butyl ester
CAS Number
101555-60-6
Purity
≥ 96%
Molecular Formula
C11H19NO4
Molecular Weight
229.27
MDL Number
MFCD06202402
PubChem ID
4018357
Appearance
White to off-white solid
Optical Rotation
[a]D25 = +27 ± 3º (C=1, CH2Cl2)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-D-β-HomoPro-OH, (R-2-Carboxymethyl-pyrrolidine-1-carboxylic acidtert-butyl ester
CAS Number
101555-60-6
Purity
≥ 96%
Molecular Formula
C11H19NO4
Molecular Weight
229.27
MDL Number
MFCD06202402
PubChem ID
4018357
Appearance
White to off-white solid
Optical Rotation
[a]D25 = +27 ± 3º (C=1, CH2Cl2)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-b-homoproline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of cyclic peptides that have enhanced stability and bioactivity.
  • Drug Development: Its unique structure allows for the design of novel pharmaceuticals, especially in the field of central nervous system disorders, where it can mimic natural amino acids.
  • Bioconjugation: Boc-D-b-homoproline can be used in bioconjugation processes, facilitating the attachment of biomolecules to drugs or diagnostic agents, improving targeting and efficacy.
  • Research in Neuroscience: The compound is instrumental in studying receptor interactions and signaling pathways, providing insights into neurological functions and potential therapeutic targets.
  • Material Science: Its properties are explored in developing new materials with specific functionalities, such as hydrogels that can be used in drug delivery systems.

Citations