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Catalog Number:
16815
CAS Number:
1175832-19-5
Fmoc-L-2,4-dinitrophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Phe(2,4-DiNO2)-OH, (S-Fmoc-2-amino-3-(2,4-dinitrophenyl)propionic acid, Fmoc-Phe(2,4-DiNO2)-OH
Documents
$72.31 /25MG
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Product Information

Fmoc-L-2,4-dinitrophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique dinitrophenyl group, which enhances its reactivity and allows for selective labeling in various biochemical applications. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group is particularly advantageous for solid-phase peptide synthesis, providing stability and ease of removal under mild conditions. Researchers appreciate its role in the synthesis of peptides with specific functionalities, enabling the exploration of new therapeutic agents and biomolecules.

In addition to its applications in peptide synthesis, Fmoc-L-2,4-dinitrophenylalanine serves as a valuable tool in the study of protein interactions and enzyme activity. The dinitrophenyl moiety can be used for spectroscopic studies, allowing scientists to monitor conformational changes in proteins or to quantify binding events. This compound's unique properties make it an essential choice for researchers looking to innovate in the fields of biochemistry and pharmaceuticals, offering a reliable pathway to develop novel compounds with enhanced biological activity.

Synonyms
Fmoc-L-Phe(2,4-DiNO2)-OH, (S-Fmoc-2-amino-3-(2,4-dinitrophenyl)propionic acid, Fmoc-Phe(2,4-DiNO2)-OH
CAS Number
1175832-19-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H19N3O8
Molecular Weight
477.42
MDL Number
MFCD08061625
PubChem ID
53398421
Appearance
White to light yellow powder
Optical Rotation
[a]D25 = +12.0 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Phe(2,4-DiNO2)-OH, (S-Fmoc-2-amino-3-(2,4-dinitrophenyl)propionic acid, Fmoc-Phe(2,4-DiNO2)-OH
CAS Number
1175832-19-5
Purity
≥ 98% (HPLC)
Molecular Formula
C24H19N3O8
Molecular Weight
477.42
MDL Number
MFCD08061625
PubChem ID
53398421
Appearance
White to light yellow powder
Optical Rotation
[a]D25 = +12.0 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-2,4-dinitrophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions and improving yields in complex peptide chains.
  • Analytical Chemistry: It is used in various analytical techniques, including chromatography, to help separate and identify amino acids and peptides due to its distinct properties.
  • Drug Development: Researchers leverage its unique structure to design and test novel pharmaceutical compounds, particularly in the development of targeted therapies.
  • Bioconjugation: This chemical is useful in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Research in Immunology: It aids in the study of immune responses by serving as a model compound for understanding how modifications affect antigenicity and immune recognition.

Citations