Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
17101
CAS Number:
475102-13-7
1-Boc-5-bromo-1H-indole-2-boronic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
5-Bromo-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronicacid, N-tert-Butoxycarbonyl-5-bromo-1H-indole-2-boronicacid
Documents
$18.53 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

1-Boc-5-bromo-1H-indole-2-boronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative features a bromo substituent, enhancing its reactivity and making it a valuable building block for the development of complex molecules. Its unique structure allows for applications in the synthesis of various pharmaceuticals, particularly in the creation of indole-based compounds, which are known for their biological activity. Researchers appreciate its role in Suzuki coupling reactions, enabling the formation of carbon-carbon bonds that are essential in drug discovery and development.

The compound's stability and ease of handling make it an attractive option for both academic and industrial laboratories. Its ability to participate in cross-coupling reactions expands its utility in creating diverse chemical libraries, which are crucial for screening potential drug candidates. With its favorable properties, 1-Boc-5-bromo-1H-indole-2-boronic acid stands out as a key reagent for chemists aiming to innovate in the fields of pharmaceuticals and materials science.

Synonyms
5-Bromo-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronicacid, N-tert-Butoxycarbonyl-5-bromo-1H-indole-2-boronicacid
CAS Number
475102-13-7
Purity
≥ 99% (HPLC)
Molecular Formula
C13H15BBrNO4
Molecular Weight
339.98
MDL Number
MFCD03701683
PubChem ID
2794714
Melting Point
108-114 ºC
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
5-Bromo-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronicacid, N-tert-Butoxycarbonyl-5-bromo-1H-indole-2-boronicacid
CAS Number
475102-13-7
Purity
≥ 99% (HPLC)
Molecular Formula
C13H15BBrNO4
Molecular Weight
339.98
MDL Number
MFCD03701683
PubChem ID
2794714
Melting Point
108-114 ºC
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-Boc-5-bromo-1H-indole-2-boronic acid is widely utilized in research focused on:

  • Drug Discovery: This compound serves as a crucial building block in the synthesis of indole-based pharmaceuticals, which are known for their diverse biological activities, including anti-cancer properties.
  • Organic Synthesis: It is employed in various organic reactions, such as Suzuki coupling, to create complex molecules, allowing chemists to develop new materials and compounds efficiently.
  • Bioconjugation: The boronic acid functionality enables selective binding to diols, making it useful in bioconjugation techniques for labeling biomolecules, which is essential in diagnostics and therapeutic applications.
  • Material Science: This compound can be used in the development of advanced materials, including polymers and nanomaterials, due to its unique chemical properties, which enhance material performance.
  • Research in Catalysis: It plays a role in catalysis research, particularly in the development of new catalytic systems that can improve reaction efficiencies and selectivity in various chemical processes.

Citations