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Catalog Number:
17597
CAS Number:
475102-14-8
1-Boc-5-methyl-1H-indole-2-boronic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
N-tert-Butoxycarbonyl-5-methyl-1H-indole-2-boronic acid
Documents
$81.92 /250MG
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Product Information

1-Boc-5-methyl-1H-indole-2-boronic acid is a versatile compound that plays a significant role in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valuable for researchers focusing on the development of pharmaceuticals and agrochemicals. Its unique structure allows for the formation of stable complexes with various substrates, making it an essential building block in Suzuki-Miyaura cross-coupling reactions. This reaction is widely utilized in the synthesis of biaryl compounds, which are crucial in the development of numerous biologically active molecules.

The compound's Boc (tert-butyloxycarbonyl) protecting group enhances its stability and solubility, facilitating its use in complex synthetic pathways. Researchers have successfully employed 1-Boc-5-methyl-1H-indole-2-boronic acid in the synthesis of novel indole derivatives, which have shown promising activity in various biological assays. Its application in the pharmaceutical industry is particularly noteworthy, as it aids in the creation of compounds with potential therapeutic effects. With its robust performance in synthetic applications, this compound is an excellent choice for professionals seeking reliable and effective reagents for their research and development projects.

Synonyms
N-tert-Butoxycarbonyl-5-methyl-1H-indole-2-boronic acid
CAS Number
475102-14-8
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18BNO4
Molecular Weight
275.11
MDL Number
MFCD04114580
PubChem ID
3863265
Melting Point
116-122 °C
Appearance
White solid
Conditions
Store at 0-8°C
General Information
Synonyms
N-tert-Butoxycarbonyl-5-methyl-1H-indole-2-boronic acid
CAS Number
475102-14-8
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18BNO4
Molecular Weight
275.11
MDL Number
MFCD04114580
PubChem ID
3863265
Melting Point
116-122 °C
Appearance
White solid
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-Boc-5-methyl-1H-indole-2-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial intermediate in the synthesis of various pharmaceuticals, particularly in developing drugs targeting cancer and other diseases due to its unique boronic acid functionality.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki reactions, to form carbon-carbon bonds, which are essential in creating complex organic molecules.
  • Material Science: The compound can be used to modify polymers and create new materials with enhanced properties, making it valuable in the development of advanced materials for electronics and coatings.
  • Bioconjugation: Its boronic acid group allows for selective binding to diols, making it useful in bioconjugation techniques for labeling biomolecules in research and diagnostics.
  • Research on Indole Derivatives: This compound is significant in studying indole derivatives, which are important in medicinal chemistry due to their wide range of biological activities.

Citations