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Catalog Number:
17902
CAS Number:
475102-11-5
1-Boc-4-chloro-2-indoleboronic acid
Purity:
≥ 97% (HPLC)
Synonym(s):
4-Chloro-N-(Boc)-indole-2-boronic acid, 1-(tert-Butoxycarbonyl)-4-chloro-1H-indol-2-ylboronic acid
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$43.87 /1G
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Product Information

1-Boc-4-chloro-2-indoleboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound features a unique combination of a boronic acid functional group and an indole structure, making it an essential building block for the development of pharmaceuticals and agrochemicals. Its ability to participate in Suzuki-Miyaura cross-coupling reactions allows for the formation of carbon-carbon bonds, facilitating the synthesis of complex organic molecules. Researchers appreciate its stability and ease of handling, which enhances its applicability in various synthetic pathways.

In addition to its synthetic utility, 1-Boc-4-chloro-2-indoleboronic acid has shown potential in the development of targeted therapies, particularly in oncology, where boron-containing compounds are being explored for their unique properties in boron neutron capture therapy (BNCT). Its selective reactivity and functionalization capabilities make it a valuable asset for chemists looking to innovate in drug design and development. With its broad range of applications, this compound stands out as a key ingredient for advancing research in both academic and industrial settings.

Synonyms
4-Chloro-N-(Boc)-indole-2-boronic acid, 1-(tert-Butoxycarbonyl)-4-chloro-1H-indol-2-ylboronic acid
CAS Number
475102-11-5
Purity
≥ 97% (HPLC)
Molecular Formula
C13H15BClNO4
Molecular Weight
295.53
MDL Number
MFCD04114582
PubChem ID
11033775
Appearance
White solid
Conditions
Store at 0-8 °C
General Information
Synonyms
4-Chloro-N-(Boc)-indole-2-boronic acid, 1-(tert-Butoxycarbonyl)-4-chloro-1H-indol-2-ylboronic acid
CAS Number
475102-11-5
Purity
≥ 97% (HPLC)
Molecular Formula
C13H15BClNO4
Molecular Weight
295.53
MDL Number
MFCD04114582
PubChem ID
11033775
Appearance
White solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1-Boc-4-chloro-2-indoleboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents due to its ability to inhibit specific enzymes.
  • Bioconjugation: It is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other compounds, enhancing drug delivery systems and targeted therapies.
  • Organic Synthesis: The compound is valuable in organic synthesis, particularly in creating complex molecules through cross-coupling reactions, which are essential in producing new materials and chemicals.
  • Material Science: Its unique properties make it suitable for developing advanced materials, such as polymers and nanomaterials, which have applications in electronics and coatings.
  • Research in Chemical Biology: It is utilized in chemical biology studies to probe biological systems, helping scientists understand cellular processes and develop new therapeutic strategies.

Citations