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Catalog Number:
31669
CAS Number:
2237216-64-5
Fmoc-(3R,4S-4-amino-3-hydroxy-5-methyl-hexanoic acid
Purity:
≥ 98% (HPLC)
Documents
$65.40 /25MG
Pack Size Availability Price
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Product Information

Fmoc-(3R,4S)-4-amino-3-hydroxy-5-methyl-hexanoic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino acids during solid-phase peptide synthesis. Its unique stereochemistry and functional groups make it an excellent candidate for the development of bioactive peptides and pharmaceuticals. Researchers appreciate its stability under various reaction conditions, allowing for efficient coupling reactions and facilitating the synthesis of complex peptide structures.

In addition to its applications in peptide synthesis, Fmoc-(3R,4S)-4-amino-3-hydroxy-5-methyl-hexanoic acid has shown potential in the development of therapeutic agents targeting various biological pathways. Its hydroxyl and amino functionalities enhance solubility and bioavailability, making it suitable for drug formulation. This compound stands out for its ability to improve the pharmacokinetic properties of peptide-based drugs, offering researchers a valuable tool in drug discovery and development.

CAS Number
2237216-64-5
Purity
≥ 98% (HPLC)
Molecular Formula
C22H25NO5
Molecular Weight
383.44
MDL Number
MFCD30749168
PubChem ID
4712556
Appearance
White powder
Optical Rotation
[a]20D = +12.2 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
CAS Number
2237216-64-5
Purity
≥ 98% (HPLC)
Molecular Formula
C22H25NO5
Molecular Weight
383.44
MDL Number
MFCD30749168
PubChem ID
4712556
Appearance
White powder
Optical Rotation
[a]20D = +12.2 ± 1 ° (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(3R,4S)-4-amino-3-hydroxy-5-methyl-hexanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting the overall structure.
  • Drug Development: It plays a critical role in the design of peptide-based pharmaceuticals, enhancing the stability and bioavailability of therapeutic agents.
  • Bioconjugation: Researchers use it to facilitate the attachment of peptides to other biomolecules, which is essential in creating targeted drug delivery systems.
  • Protein Engineering: The compound aids in the development of modified proteins with enhanced properties, useful in biotechnology applications such as enzyme production.
  • Research in Neuroscience: It is utilized in the synthesis of neuropeptides, contributing to studies aimed at understanding neurological functions and potential treatments for disorders.

Citations