Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
31675
CAS Number:
1312674-57-9
Fmoc-trans-4-methylthio-Pro-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
(2S,4R)-Fmoc-4-methylthio-pyrrolidine-2-carboxylic acid
Documents
$86.23 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-trans-4-methylthio-Pro-OH is a valuable compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure, characterized by the presence of a methylthio group, enhances its reactivity and stability, making it an ideal choice for researchers focused on developing complex peptide sequences.

This compound is particularly beneficial in the field of medicinal chemistry, where it serves as a building block for the synthesis of bioactive peptides and pharmaceuticals. Its application extends to the production of peptide-based therapeutics, which are increasingly important in treating various diseases, including cancer and metabolic disorders. The ability to incorporate Fmoc-trans-4-methylthio-Pro-OH into peptide chains allows for the creation of more stable and effective drug candidates, providing researchers with a powerful tool in their quest for innovative treatments.

Synonyms
(2S,4R)-Fmoc-4-methylthio-pyrrolidine-2-carboxylic acid
CAS Number
1312674-57-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO4S
Molecular Weight
383.46
MDL Number
MFCD30749171
Appearance
White powder
Optical Rotation
[a]D20 = -28 ± 2° (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
(2S,4R)-Fmoc-4-methylthio-pyrrolidine-2-carboxylic acid
CAS Number
1312674-57-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO4S
Molecular Weight
383.46
MDL Number
MFCD30749171
Appearance
White powder
Optical Rotation
[a]D20 = -28 ± 2° (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-trans-4-methylthio-Pro-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial in developing complex peptides used in pharmaceuticals.
  • Drug Development: Its role in creating peptide-based drugs enables researchers to design more effective therapeutic agents, particularly in targeting specific diseases, such as cancer or diabetes.
  • Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules to create targeted drug delivery systems. This enhances the efficacy and reduces side effects of medications.
  • Research in Protein Engineering: It aids in the modification of proteins, allowing scientists to study protein interactions and functions, which is vital for understanding biological processes and developing new treatments.
  • Analytical Chemistry: Fmoc-trans-4-methylthio-Pro-OH is employed in various analytical techniques, such as chromatography, to help identify and quantify peptide compositions in complex mixtures.

Citations