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Catalog Number:
31879
Fmoc-D-Agb(Pbf,Boc)-OH
Purity:
≥ 98% (TLC)
Synonym(s):
2-(Fmoc-amino)-4-(N-Pbf, N'-Boc-guanidino)-D-butyric acid, Fmoc-D-Nar(Pbf,Boc)-OH
Documents
$113.87 /100MG
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Product Information

Fmoc-D-Agb(Pbf,Boc)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. The presence of Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran) and Boc (tert-butyloxycarbonyl) groups enhances its stability and solubility, making it an ideal choice for researchers in the fields of medicinal chemistry and biochemistry.

This compound is particularly valuable in the synthesis of complex peptides and proteins, facilitating the development of therapeutic agents and biologically active molecules. Its unique structure allows for efficient coupling reactions, leading to higher yields and purities in peptide synthesis compared to similar compounds. Researchers can leverage Fmoc-D-Agb(Pbf,Boc)-OH for applications in drug discovery, vaccine development, and the creation of novel biomaterials, making it an essential tool in modern chemical research.

Synonyms
2-(Fmoc-amino)-4-(N-Pbf, N'-Boc-guanidino)-D-butyric acid, Fmoc-D-Nar(Pbf,Boc)-OH
Purity
≥ 98% (TLC)
Molecular Formula
C38H46N4O9S
Molecular Weight
734.9
MDL Number
MFCD13184918
Melting Point
87 - 90?C
Appearance
White powder
Optical Rotation
[a]D20 = + 5.5 ± 1° (C=1 in MeOH), no corrected to net substance
Conditions
Store at 0-8°C
General Information
Synonyms
2-(Fmoc-amino)-4-(N-Pbf, N'-Boc-guanidino)-D-butyric acid, Fmoc-D-Nar(Pbf,Boc)-OH
Purity
≥ 98% (TLC)
Molecular Formula
C38H46N4O9S
Molecular Weight
734.9
MDL Number
MFCD13184918
Melting Point
87 - 90?C
Appearance
White powder
Optical Rotation
[a]D20 = + 5.5 ± 1° (C=1 in MeOH), no corrected to net substance
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Agb(Pbf,Boc)-OH is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Drug Discovery: Its application in drug discovery enables the design of novel therapeutic agents, particularly in targeting specific biological pathways, enhancing the efficiency of the drug development process.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of biomolecules to drugs or diagnostic agents, which improves the specificity and efficacy of treatments.
  • Research in Cancer Therapy: Researchers utilize this compound to develop targeted cancer therapies, allowing for the creation of compounds that can selectively attack cancer cells while sparing healthy tissue.
  • Protein Engineering: Its role in protein engineering helps in modifying proteins to enhance their stability and activity, which is crucial for developing biopharmaceuticals and industrial enzymes.

Citations