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Catalog Number:
37736
CAS Number:
154361-50-9
Capecitabine
Grade:
meets USP specification
Purity:
98 - 102% (Assay, on anhydrous basis)
Synonym(s):
5'-Deoxy-5-fluoro-N4-[(pentyloxy)carbonyl]cytidine
Documents
$35.00 /1G
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Product Information

Capecitabine is an innovative chemotherapeutic agent primarily utilized in the treatment of various cancers, including colorectal and breast cancer. As a prodrug, it is metabolized into 5-fluorouracil (5-FU) in the body, allowing for targeted action against cancer cells while minimizing damage to healthy tissues. This selective activation enhances its efficacy and reduces side effects compared to traditional chemotherapy agents. Capecitabine's oral administration offers convenience and improved patient compliance, making it a preferred choice in oncology.

In addition to its primary applications, Capecitabine is also being explored in combination therapies, enhancing the effectiveness of other anticancer drugs. Its unique mechanism of action, which involves the inhibition of thymidylate synthase, positions it as a vital component in personalized cancer treatment regimens. Researchers and healthcare professionals appreciate Capecitabine for its ability to provide a more tailored approach to cancer therapy, ultimately leading to better patient outcomes.

Synonyms
5'-Deoxy-5-fluoro-N4-[(pentyloxy)carbonyl]cytidine
CAS Number
154361-50-9
Purity
98 - 102% (Assay, on anhydrous basis)
Grade
meets USP specification
Molecular Formula
C15H22FN3O6
Molecular Weight
359.35
MDL Number
MFCD00930626
PubChem ID
400633
Melting Point
123 °C (dec.)
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = 96 - 100 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5'-Deoxy-5-fluoro-N4-[(pentyloxy)carbonyl]cytidine
CAS Number
154361-50-9
Purity
98 - 102% (Assay, on anhydrous basis)
Grade
meets USP specification
Molecular Formula
C15H22FN3O6
Molecular Weight
359.35
MDL Number
MFCD00930626
PubChem ID
400633
Melting Point
123 °C (dec.)
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = 96 - 100 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Capecitabine is widely utilized in research focused on:

  • Cancer Treatment: Primarily used as an oral chemotherapy agent for treating breast and colorectal cancers, offering a convenient alternative to intravenous therapies.
  • Combination Therapy: Frequently combined with other chemotherapeutic agents to enhance efficacy and reduce resistance, making it a versatile option in oncology.
  • Personalized Medicine: Research is ongoing into genetic markers that predict patient response, allowing for tailored treatment plans that improve outcomes.
  • Pharmaceutical Development: Used in the formulation of new drug delivery systems, enhancing bioavailability and patient compliance due to its oral administration.
  • Clinical Trials: A key compound in numerous clinical studies aimed at optimizing cancer treatment protocols, contributing to advancements in oncology.

Citations