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Catalog Number:
46578
CAS Number:
2095208-17-4
Fmoc-Ile-(Dmb)Gly-OH
Purity:
≥ 95% (HPLC)
Synonym(s):
N-α-Fmoc-L-Isoleucyl-N-α-(2,4-dimethoxybenzyl)-glycine
Documents
$110.70 /100MG
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Product Information

Fmoc-Ile-(Dmb)Gly-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry and biochemistry for its ability to facilitate the formation of peptide bonds, making it an essential building block for the synthesis of complex peptides and proteins. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective deprotection under mild conditions, which is advantageous for researchers looking to streamline their synthesis processes.

In practical applications, Fmoc-Ile-(Dmb)Gly-OH is widely used in solid-phase peptide synthesis (SPPS), enabling the efficient assembly of peptides with high purity and yield. Its compatibility with various coupling reagents and its stability during the synthesis process make it a preferred choice among professionals in pharmaceutical and biotechnology industries. Researchers can leverage this compound to develop novel therapeutics, including peptide-based drugs and biologics, enhancing their potential for targeted treatments and improved efficacy.

Synonyms
N-α-Fmoc-L-Isoleucyl-N-α-(2,4-dimethoxybenzyl)-glycine
CAS Number
2095208-17-4
Purity
≥ 95% (HPLC)
Molecular Formula
C32H36N2O7
Molecular Weight
560.64
MDL Number
MFCD10001336
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -34 to -28 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-α-Fmoc-L-Isoleucyl-N-α-(2,4-dimethoxybenzyl)-glycine
CAS Number
2095208-17-4
Purity
≥ 95% (HPLC)
Molecular Formula
C32H36N2O7
Molecular Weight
560.64
MDL Number
MFCD10001336
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -34 to -28 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Ile-(Dmb)Gly-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective groups allow for selective reactions, making it easier to construct complex peptide chains.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. The ability to modify the structure helps in optimizing the efficacy and stability of drug candidates.
  • Bioconjugation: Researchers utilize this compound for bioconjugation processes, where it can be linked to other biomolecules. This is essential in developing targeted therapies and diagnostic agents.
  • Protein Engineering: It plays a role in modifying proteins to enhance their properties. This is particularly useful in biotechnology applications where improved enzyme activity or stability is desired.
  • Research in Cancer Therapy: The compound is explored in the development of novel cancer therapies, leveraging its ability to create peptides that can selectively target cancer cells, potentially reducing side effects compared to traditional treatments.

Citations