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Catalog Number:
47025
Fmoc-N-Me-D-Phe(4-COOtBu)-OH
Purity:
≥ 99% (Chiral HPLC)
Documents
$260.00 /100MG
Pack Size Availability Price
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Product Information

Fmoc-N-Me-D-Phe(4-COOtBu)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of amine functionalities during the synthesis of peptides. Its unique structure, including the N-methyl and t-butyl ester groups, enhances its stability and solubility, making it an ideal choice for researchers aiming to create complex peptide sequences with high purity and yield.

In the pharmaceutical industry, Fmoc-N-Me-D-Phe(4-COOtBu)-OH serves as a crucial building block for the synthesis of bioactive peptides, which can be used in therapeutic applications such as cancer treatment, hormone regulation, and antimicrobial agents. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups makes it a preferred choice among chemists. Additionally, this compound's favorable properties allow for streamlined processes in solid-phase peptide synthesis, ensuring efficiency and reliability in laboratory settings.

Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C30H31NO6
Molecular Weight
501.57
Appearance
White powder
Optical Rotation
[ॅ]D20 = 53 +/- 1 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C30H31NO6
Molecular Weight
501.57
Appearance
White powder
Optical Rotation
[ॅ]D20 = 53 +/- 1 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-N-Me-D-Phe(4-COOtBu)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex and biologically active peptides.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, enhancing the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach peptides to other molecules, improving drug delivery systems and targeting mechanisms.
  • Research in Neuroscience: It is utilized in studies related to neuropeptides, contributing to the understanding of neurological functions and the development of treatments for neurological disorders.
  • Custom Peptide Libraries: Researchers employ this compound to create diverse peptide libraries for screening and identifying novel bioactive compounds, facilitating advancements in drug discovery.

Citations