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Catalog Number:
47026
CAS Number:
210282-33-0
Fmoc-Phe(3-COOtBu)-OH
Purity:
≥ 99.5% (Chiral HPLC)
Documents
$25.00 /100MG
Pack Size Availability Price
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Product Information

Fmoc-Phe(3-COOtBu)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for the introduction of a tert-butyl ester at the 3-position of the phenyl ring, enhancing its stability and solubility in organic solvents. Researchers and industry professionals appreciate this compound for its ability to facilitate the synthesis of complex peptides, making it invaluable in the fields of medicinal chemistry and biochemistry.

The practical applications of Fmoc-Phe(3-COOtBu)-OH extend to the development of peptide-based therapeutics, where precise control over peptide sequences is crucial. Its use in solid-phase peptide synthesis (SPPS) allows for efficient and high-yield production of peptides, which can be further modified for various applications, including drug delivery systems and vaccine development. With its favorable properties and ease of use, this compound stands out as a preferred choice for researchers looking to streamline their peptide synthesis processes.

CAS Number
210282-33-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.54
MDL Number
MFCD34186936
PubChem ID
155270890
Appearance
White powder
Optical Rotation
[a]D20 = -25 ±2 °(C=1 in DMF)
Conditions
Store at RT
General Information
CAS Number
210282-33-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.54
MDL Number
MFCD34186936
PubChem ID
155270890
Appearance
White powder
Optical Rotation
[a]D20 = -25 ±2 °(C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Phe(3-COOtBu)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its protective groups facilitate the selective addition of amino acids, enhancing the overall yield and purity of the final product.
  • Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs. The ability to modify the structure easily can lead to improved efficacy and reduced side effects, making it a valuable tool in medicinal chemistry.
  • Bioconjugation: The compound is employed in bioconjugation processes, where it helps attach peptides to various biomolecules. This application is crucial in creating targeted therapies and diagnostics in biotechnology.
  • Research in Cancer Therapeutics: Its role in synthesizing peptide analogs has significant implications in cancer research, where modified peptides can be designed to target specific cancer cells, potentially leading to more effective treatments.
  • Protein Engineering: Fmoc-Phe(3-COOtBu)-OH is also used in the engineering of proteins with enhanced properties. By incorporating this compound into proteins, researchers can study structure-function relationships and develop proteins with novel functionalities.

Citations