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Catalog Number:
07386
CAS Number:
205526-27-8
Fmoc-3-trifluorometil-L-fenilalanina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-3-trifluorometil-L-fenilalanina, Fmoc-L-Phe(3-trifluorometil)-OH, Fmoc-Phe(3-CF3)-OH
Documents
$115.70 /1G
Tamaño
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Product Information

Fmoc-3-trifluoromethyl-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique trifluoromethyl group that enhances its lipophilicity and biological activity, making it an attractive choice for researchers in medicinal chemistry and biochemistry. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Its distinctive properties enable the creation of peptides with improved pharmacological profiles, which are crucial for developing novel therapeutics.

In practical applications, Fmoc-3-trifluoromethyl-L-phenylalanine is often employed in the synthesis of peptide-based drugs, particularly those targeting specific receptors or pathways in disease processes. Its ability to modify peptide properties can lead to enhanced efficacy and reduced side effects, making it a valuable tool for pharmaceutical researchers. Additionally, this compound's unique characteristics set it apart from similar amino acid derivatives, offering researchers a reliable option for advancing their projects in peptide chemistry.

Synonyms
Fmoc-3-trifluorometil-L-fenilalanina, Fmoc-L-Phe(3-trifluorometil)-OH, Fmoc-Phe(3-CF3)-OH
CAS Number
205526-27-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD00672555
PubChem ID
3295218
Melting Point
126 - 145 °C
Appearance
Polvo de color blanco a blanquecino
Optical Rotation
[a] D 20 = -34 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-3-trifluorometil-L-fenilalanina, Fmoc-L-Phe(3-trifluorometil)-OH, Fmoc-Phe(3-CF3)-OH
CAS Number
205526-27-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD00672555
PubChem ID
3295218
Melting Point
126 - 145 °C
Appearance
Polvo de color blanco a blanquecino
Optical Rotation
[a] D 20 = -34 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-trifluoromethyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and biologically active peptides.
  • Drug Development: Its unique trifluoromethyl group enhances the pharmacological properties of peptides, making it valuable in the design of new therapeutic agents in pharmaceutical research.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach peptides to other biomolecules, facilitating the development of targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the modification of proteins to study structure-function relationships, helping researchers understand protein interactions and stability.
  • Fluorine Chemistry Studies: The presence of fluorine allows for unique studies in fluorine chemistry, providing insights into the behavior of fluorinated compounds in various chemical environments.

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