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Catalog Number:
15271
CAS Number:
269396-54-5
Fmoc-2,4-dicloro-D-β-homofenilalanina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-β-HomoPhe(2,4-DiCl)-OH, Ácido Fmoc-( R -3-amino-4-(2,4-diclorofenil)butírico
Documents
$72.31 /25 mg
Tamaño
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Product Information

Fmoc-2,4-dichloro-D-b-homophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which enhances its stability and ease of use in solid-phase peptide synthesis. The presence of two chlorine atoms on the phenyl ring not only contributes to its distinctive properties but also allows for selective reactivity, making it an excellent choice for researchers looking to create complex peptide structures with precision.

In the pharmaceutical industry, Fmoc-2,4-dichloro-D-b-homophenylalanine serves as a crucial building block for the development of therapeutic peptides, particularly those targeting specific biological pathways. Its application extends to the synthesis of peptide-based drugs, where its unique structural features can lead to improved efficacy and specificity. Researchers appreciate its compatibility with various coupling reagents and its ability to facilitate the synthesis of peptides with diverse functionalities, making it an essential tool in modern medicinal chemistry.

Synonyms
Fmoc-D-β-HomoPhe(2,4-DiCl)-OH, Ácido Fmoc-( R -3-amino-4-(2,4-diclorofenil)butírico
CAS Number
269396-54-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C25H21Cl2NO4
Molecular Weight
470.35
MDL Number
MFCD01860947
PubChem ID
53397928
Appearance
Polvo blanco
Optical Rotation
[a] D 25 = +42° a 61,5º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-D-β-HomoPhe(2,4-DiCl)-OH, Ácido Fmoc-( R -3-amino-4-(2,4-diclorofenil)butírico
CAS Number
269396-54-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C25H21Cl2NO4
Molecular Weight
470.35
MDL Number
MFCD01860947
PubChem ID
53397928
Appearance
Polvo blanco
Optical Rotation
[a] D 25 = +42° a 61,5º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2,4-dichloro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide structures efficiently.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing novel therapeutics, especially in designing peptide-based drugs that target specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to drugs or imaging agents, enhancing their efficacy and specificity in targeted therapies.
  • Research in Cancer Therapeutics: Its applications extend to cancer research, where it aids in the development of peptide inhibitors that can selectively target cancer cells, improving treatment outcomes.
  • Protein Engineering: This compound is valuable in protein engineering, allowing scientists to modify proteins for better stability or activity, which is crucial for various biotechnological applications.

Citas