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Catalog Number:
15576
CAS Number:
507472-19-7
Ácido Fmoc-( S )-3-amino-3-(2-trifluorometilfenil)propiónico
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-β-Phe(2-CF3)-OH, ( S )-Fmoc-2-trifluorometil-β-fenilalanina
Documents
$35.30 /100 mg
Tamaño
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Product Information

Fmoc-(S)-3-amino-3-(2-trifluoromethylphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique trifluoromethylphenyl side chain enhances lipophilicity and biological activity, making it an excellent candidate for the development of novel therapeutics.

Researchers and industry professionals can leverage this compound in the design of peptides with improved pharmacological properties, particularly in drug discovery and development. Its ability to facilitate the formation of complex peptide structures while maintaining stability under various conditions makes it invaluable in the pharmaceutical industry. Additionally, the trifluoromethyl group can impart unique electronic properties, potentially leading to enhanced interactions with biological targets. This compound stands out for its efficiency in streamlining peptide synthesis, ultimately accelerating research timelines and improving outcomes in drug development.

Synonyms
Fmoc-L-β-Phe(2-CF3)-OH, ( S )-Fmoc-2-trifluorometil-β-fenilalanina
CAS Number
507472-19-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428001
PubChem ID
24902251
Appearance
Sólido blanco
Optical Rotation
[a] D 20 = -9,8 ± 2 ° (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-L-β-Phe(2-CF3)-OH, ( S )-Fmoc-2-trifluorometil-β-fenilalanina
CAS Number
507472-19-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428001
PubChem ID
24902251
Appearance
Sólido blanco
Optical Rotation
[a] D 20 = -9,8 ± 2 ° (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(2-trifluoromethylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure enhances the design of novel pharmaceuticals, especially in the development of drugs targeting specific receptors, thanks to its ability to modulate biological activity.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules for therapeutic applications, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: It plays a role in studying neuropeptides, contributing to the understanding of neurological pathways and potential treatments for neurological disorders.
  • Fluorinated Compounds: The trifluoromethyl group enhances lipophilicity, making it valuable in the synthesis of fluorinated compounds that are often more effective in biological systems compared to their non-fluorinated counterparts.

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