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Catalog Number:
29903
CAS Number:
50-76-0
Actinomicina D de especies de Streptomyces
Grade:
cumple con las especificaciones USP
Purity:
≥ 98 % (HPLC)
Synonym(s):
Dactinomicina, Actinomicina C1
Hazmat
Antibiotic
Documents
$35.00 /5 mg
Tamaño
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Product Information

Actinomycin D is a potent antibiotic and antineoplastic agent renowned for its ability to inhibit RNA synthesis, making it invaluable in cancer research and treatment. This compound is primarily utilized in the pharmaceutical industry for its effectiveness against various types of tumors, including Wilms' tumor and rhabdomyosarcoma. Its mechanism of action involves intercalating into DNA, thereby preventing the transcription process, which is crucial for cell proliferation. Researchers also leverage Actinomycin D in molecular biology studies to explore gene expression and cellular responses, providing insights into cancer biology and therapeutic strategies.

In addition to its applications in oncology, Actinomycin D serves as a critical tool in the development of novel therapeutic agents and in the study of cellular mechanisms. Its unique properties, such as high potency and specificity, distinguish it from other chemotherapeutic agents, making it a preferred choice in both clinical and laboratory settings. With ongoing research, the potential uses of Actinomycin D continue to expand, offering promising avenues for innovative treatments and scientific discoveries.

Synonyms
Dactinomicina, Actinomicina C1
CAS Number
50-76-0
Purity
≥ 98 % (HPLC)
Grade
cumple con las especificaciones USP
Molecular Formula
C62H86N12O16
Molecular Weight
1255.42
MDL Number
MFCD00005033
PubChem ID
2019
Melting Point
243 - 248 °C
Appearance
Polvo cristalino de color rojo brillante
Optical Rotation
[a] D 20 = -292 a -317°
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Dactinomicina, Actinomicina C1
CAS Number
50-76-0
Purity
≥ 98 % (HPLC)
Grade
cumple con las especificaciones USP
Molecular Formula
C62H86N12O16
Molecular Weight
1255.42
MDL Number
MFCD00005033
PubChem ID
2019
Melting Point
243 - 248 °C
Appearance
Polvo cristalino de color rojo brillante
Optical Rotation
[a] D 20 = -292 a -317°
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Antibiotic
DEA-regulated
No
Warnings
-
Applications

Actinomycin D is widely utilized in research focused on:

  • Cancer Treatment: This compound is a potent chemotherapeutic agent used to treat various cancers, including Wilms' tumor and rhabdomyosarcoma, by inhibiting DNA transcription.
  • Cell Biology Studies: Researchers use Actinomycin D to study gene expression and cellular responses, as it effectively blocks RNA synthesis, allowing scientists to investigate the role of specific genes.
  • Antibiotic Research: Actinomycin D has applications in microbiology as it exhibits antibiotic properties, helping researchers explore new antimicrobial therapies against resistant strains.
  • Development of Anticancer Drugs: The compound serves as a lead structure in the design of new anticancer agents, providing insights into structure-activity relationships that can enhance drug efficacy.
  • Biochemical Research: It is frequently used in studies involving protein synthesis and cellular metabolism, allowing scientists to dissect complex biological pathways and mechanisms.

Citas