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Catalog Number:
31876
CAS Number:
1333332-17-4
Fmoc-HomoSer(TBDMS)-OH
Purity:
≥ 99 % (HPLC quiral)
Temperature Sensitive
Documents
$95.84 /100 mg
Tamaño
Request Bulk Quote
Product Information

Fmoc-HomoSer(TBDMS)-OH is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which is widely recognized for its effectiveness in solid-phase peptide synthesis, allowing for the selective protection of amino groups. The incorporation of the TBDMS (tert-butyldimethylsilyl) group enhances the stability and solubility of the compound, making it particularly useful in various organic synthesis applications. Researchers and industry professionals can leverage this compound for the development of peptide-based therapeutics, where precise control over amino acid sequences is essential.

The unique combination of protective groups in Fmoc-HomoSer(TBDMS)-OH not only facilitates the synthesis of complex peptides but also improves the overall yield and purity of the final products. Its application extends to the fields of biochemistry and medicinal chemistry, where it aids in the exploration of novel drug candidates and the design of biomolecules with enhanced biological activity. With its robust properties and practical applications, Fmoc-HomoSer(TBDMS)-OH is an invaluable tool for researchers aiming to innovate in peptide chemistry.

CAS Number
1333332-17-4
Purity
≥ 99 % (HPLC quiral)
Molecular Formula
C25H33NO5Si
Molecular Weight
455.62
MDL Number
MFCD30529785
PubChem ID
138108034
Melting Point
89 - 92 °C
Appearance
Polvo de color blanco a blanquecino
Optical Rotation
[a] D 20 = -26 ± 2 º (C=1 en DMF)
Conditions
Conservar a -18 °C
General Information
CAS Number
1333332-17-4
Purity
≥ 99 % (HPLC quiral)
Molecular Formula
C25H33NO5Si
Molecular Weight
455.62
MDL Number
MFCD30529785
PubChem ID
138108034
Melting Point
89 - 92 °C
Appearance
Polvo de color blanco a blanquecino
Optical Rotation
[a] D 20 = -26 ± 2 º (C=1 en DMF)
Conditions
Conservar a -18 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-HomoSer(TBDMS)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It is used in the development of therapeutic peptides, enabling researchers to modify and optimize peptide sequences for better efficacy and stability in pharmaceutical applications.
  • Bioconjugation: The compound facilitates bioconjugation techniques, which are essential for attaching biomolecules to drugs or imaging agents, enhancing their targeting capabilities in medical diagnostics.
  • Research in Proteomics: It plays a role in proteomics studies, helping scientists to analyze protein interactions and functions by providing modified amino acids for labeling and detection.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to specific research needs, which allows for flexibility and innovation in experimental designs.

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