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Catalog Number:
37604
CAS Number:
136470-78-5
Abacavir
Purity:
≥ 99,2 % (HPLC)
Synonym(s):
(1S,4R)-4-[2-Amino-6-(ciclopropilamino)-9H -purin -9-il]-2-ciclopenteno-1-metanol
Documents
$157.64 /1G
Tamaño
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Product Information

Abacavir is a potent antiretroviral medication primarily used in the treatment of HIV infection. This compound belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and is known for its ability to inhibit viral replication effectively. Abacavir is particularly valuable in combination therapies, enhancing the efficacy of treatment regimens and improving patient outcomes. Its unique structure allows for a favorable pharmacokinetic profile, making it a preferred choice for many healthcare providers.

In clinical settings, Abacavir has demonstrated significant benefits in reducing viral load and increasing CD4 cell counts, which are crucial for maintaining immune function in HIV-positive patients. Its application extends beyond HIV treatment, as ongoing research explores its potential in other viral infections and therapeutic areas. With a well-established safety profile and a history of successful use, Abacavir remains a critical component in the fight against HIV, offering hope and improved quality of life for those affected.

Synonyms
(1S,4R)-4-[2-Amino-6-(ciclopropilamino)-9H -purin -9-il]-2-ciclopenteno-1-metanol
CAS Number
136470-78-5
Purity
≥ 99,2 % (HPLC)
Molecular Formula
C14H18N6O
Molecular Weight
286.34
MDL Number
MFCD00903850
PubChem ID
1971
Melting Point
161 °C (descenso)
Appearance
Polvo cristalino de color blanquecino a rosado.
Optical Rotation
[a]20D = -53 a -56 ° (C=0,15 en MeOH)
Conditions
Tienda en RT
General Information
Synonyms
(1S,4R)-4-[2-Amino-6-(ciclopropilamino)-9H -purin -9-il]-2-ciclopenteno-1-metanol
CAS Number
136470-78-5
Purity
≥ 99,2 % (HPLC)
Molecular Formula
C14H18N6O
Molecular Weight
286.34
MDL Number
MFCD00903850
PubChem ID
1971
Melting Point
161 °C (descenso)
Appearance
Polvo cristalino de color blanquecino a rosado.
Optical Rotation
[a]20D = -53 a -56 ° (C=0,15 en MeOH)
Conditions
Tienda en RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Abacavir is widely utilized in research focused on:

  • HIV Treatment: It is a key antiretroviral medication used in combination therapies for treating HIV, helping to reduce viral load and improve immune function.
  • Personalized Medicine: Genetic testing for HLA-B*5701 can identify patients at risk for hypersensitivity reactions, allowing for safer prescribing practices.
  • Clinical Research: Abacavir is often studied in clinical trials to assess its efficacy and safety in various populations, contributing to advancements in HIV treatment protocols.
  • Pharmaceutical Development: Its unique mechanism of action as a nucleoside reverse transcriptase inhibitor makes it a valuable compound in the development of new antiviral drugs.
  • Combination Therapies: Used in fixed-dose combinations with other antiretrovirals, it simplifies treatment regimens, improving adherence among patients.

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