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Catalog Number:
41350
CAS Number:
203866-16-4
Éster metílico de N- Boc- cis -4-fluoro-L-prolina
Purity:
≥ 96,5 % (HPLC)
Synonym(s):
(2 S ,4 S )-1- terc -Butil-2-metil-4-fluoropirrolidin-1,2-dicarboxilato, Metil-(2 S ,4 S )- N -Boc-4-fluoropirrolidin-2-carboxilato
Documents
$138.71 /500 mg
Tamaño
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Product Information

N-Boc-cis-4-Fluoro-L-proline methyl ester is a valuable compound in the field of medicinal chemistry and pharmaceutical research. This derivative of proline features a tert-butyl carbamate protecting group and a methyl ester, making it an ideal building block for the synthesis of various bioactive molecules. Its unique fluorinated structure enhances its potential as a chiral auxiliary in asymmetric synthesis, allowing researchers to create compounds with specific stereochemical configurations.

This compound is particularly relevant for the development of peptide-based therapeutics and can be utilized in the synthesis of novel inhibitors or modulators in drug discovery processes. Its stability and ease of modification make it a preferred choice for chemists looking to explore new avenues in medicinal applications. Additionally, N-Boc-cis-4-Fluoro-L-proline methyl ester can serve as a key intermediate in the preparation of fluorinated amino acids, which are increasingly important in the design of pharmaceuticals with improved efficacy and reduced side effects.

Synonyms
(2 S ,4 S )-1- terc -Butil-2-metil-4-fluoropirrolidin-1,2-dicarboxilato, Metil-(2 S ,4 S )- N -Boc-4-fluoropirrolidin-2-carboxilato
CAS Number
203866-16-4
Purity
≥ 96,5 % (HPLC)
Molecular Formula
C 11 H 18 FNO
Molecular Weight
247.26
MDL Number
MFCD11054130
PubChem ID
11608471
Density
1,153 g/mL a 25 °C
Appearance
De incoloro a amarillo a tostado
Refractive Index
n20D = 1,448
Optical Rotation
[α] 20 D = -74 a -60 ° (C = 0,5 en MeOH)
Conditions
Tienda en RT
General Information
Synonyms
(2 S ,4 S )-1- terc -Butil-2-metil-4-fluoropirrolidin-1,2-dicarboxilato, Metil-(2 S ,4 S )- N -Boc-4-fluoropirrolidin-2-carboxilato
CAS Number
203866-16-4
Purity
≥ 96,5 % (HPLC)
Molecular Formula
C 11 H 18 FNO
Molecular Weight
247.26
MDL Number
MFCD11054130
PubChem ID
11608471
Density
1,153 g/mL a 25 °C
Appearance
De incoloro a amarillo a tostado
Refractive Index
n20D = 1,448
Optical Rotation
[α] 20 D = -74 a -60 ° (C = 0,5 en MeOH)
Conditions
Tienda en RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Boc-cis-4-Fluoro-L-proline methyl ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the creation of peptide-based drugs that target specific biological pathways.
  • Protein Engineering: It is employed in the design of modified peptides and proteins, enhancing their stability and activity, which is vital for drug formulation and therapeutic applications.
  • Research in Neuroscience: The compound is used in studies investigating neuroactive peptides, helping researchers understand their role in neurological disorders and potential treatments.
  • Material Science: Its unique properties make it suitable for developing new materials, including polymers that can be used in drug delivery systems, improving the efficacy of treatments.
  • Biotechnology: This chemical is instrumental in the production of biocatalysts, which are essential for various industrial processes, offering a more sustainable approach compared to traditional chemical methods.

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