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Catalog Number:
05119
CAS Number:
198543-96-3
Fmoc-D-2-cyclohexylglycine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-D-Chg-OH, Fmoc-cyclohexyl-D-Gly-OH, Fmoc-D-Phg(hexahydro)-OH
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Product Information

Fmoc-D-2-cyclohexylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique cyclohexyl side chain that enhances the hydrophobic interactions in peptides, making it particularly valuable in the design of bioactive compounds. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Researchers and industry professionals appreciate its role in developing peptide-based therapeutics, where precise control over structure and function is crucial.

This compound is especially beneficial in the pharmaceutical industry for creating peptides with improved solubility and bioavailability. Its unique properties facilitate the synthesis of cyclic peptides and other complex structures, which are often used in drug discovery and development. With its ability to enhance the pharmacokinetic profiles of peptides, Fmoc-D-2-cyclohexylglycine stands out as a key building block for innovative therapeutic solutions.

Synonyms
Fmoc-D-Chg-OH, Fmoc-cyclohexyl-D-Gly-OH, Fmoc-D-Phg(hexahydro)-OH
CAS Number
198543-96-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C 23 H 25 NON 4
Molecular Weight
379.4
MDL Number
MFCD00190877
PubChem ID
2817527
Melting Point
167 - 182 °C
Appearance
Poudre blanche
Optical Rotation
[a] 20 D = -5 ± 1 ° (C=3 dans MeOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-D-Chg-OH, Fmoc-cyclohexyl-D-Gly-OH, Fmoc-D-Phg(hexahydro)-OH
CAS Number
198543-96-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C 23 H 25 NON 4
Molecular Weight
379.4
MDL Number
MFCD00190877
PubChem ID
2817527
Melting Point
167 - 182 °C
Appearance
Poudre blanche
Optical Rotation
[a] 20 D = -5 ± 1 ° (C=3 dans MeOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-D-2-cyclohexylglycine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structural properties make it valuable in the pharmaceutical industry for developing novel drug candidates, especially those targeting specific receptors or enzymes.
  • Bioconjugation: Fmoc-D-2-cyclohexylglycine can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies.
  • Research in Neuroscience: This compound is employed in studies related to neuropeptides, helping researchers understand their role in neurological functions and potential therapeutic applications.
  • Custom Peptide Libraries: It is instrumental in the creation of custom peptide libraries for screening in drug discovery, enabling researchers to identify potential leads more efficiently.

Citations