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Catalog Number:
07385
CAS Number:
82317-82-6
Boc-3-trifluorométhyl-D-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-D-Phe(3-CF3)-OH, Boc-D-Phe(3-trifluorométhyl)-OH, ( Acide R -2- tert -Butoxycarbonylamino-3-(3-trifluorométhyl-phényl)propionique
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$103.56 /1G
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Product Information

Boc-3-trifluoromethyl-D-phenylalanine is a valuable amino acid derivative known for its unique trifluoromethyl group, which enhances its lipophilicity and metabolic stability. This compound is particularly relevant in pharmaceutical research and development, where it serves as a crucial building block for the synthesis of peptide-based therapeutics. Its Boc (tert-butyloxycarbonyl) protecting group allows for selective deprotection, facilitating the incorporation of this amino acid into complex peptide sequences. Researchers have utilized Boc-3-trifluoromethyl-D-phenylalanine in the design of novel drug candidates, particularly in the development of inhibitors targeting various biological pathways.

In addition to its applications in drug discovery, this compound is also employed in the synthesis of advanced materials and agrochemicals, where the trifluoromethyl moiety can impart desirable properties such as increased potency and selectivity. The unique characteristics of Boc-3-trifluoromethyl-D-phenylalanine make it an essential tool for chemists and researchers aiming to innovate in their respective fields, providing them with the versatility needed for cutting-edge applications.

Synonyms
Boc-D-Phe(3-CF3)-OH, Boc-D-Phe(3-trifluorométhyl)-OH, ( Acide R -2- tert -Butoxycarbonylamino-3-(3-trifluorométhyl-phényl)propionique
CAS Number
82317-82-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C 15 H 18 F 3 NON 4
Molecular Weight
333.31
MDL Number
MFCD00672525
PubChem ID
4678092
Melting Point
136 - 138 °C
Appearance
Poudre blanche
Optical Rotation
[a] 25 D = -6,3 ± 1 º (C=1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Boc-D-Phe(3-CF3)-OH, Boc-D-Phe(3-trifluorométhyl)-OH, ( Acide R -2- tert -Butoxycarbonylamino-3-(3-trifluorométhyl-phényl)propionique
CAS Number
82317-82-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C 15 H 18 F 3 NON 4
Molecular Weight
333.31
MDL Number
MFCD00672525
PubChem ID
4678092
Melting Point
136 - 138 °C
Appearance
Poudre blanche
Optical Rotation
[a] 25 D = -6,3 ± 1 º (C=1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-3-trifluoromethyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the pharmaceutical industry, where it aids in the development of novel therapeutic agents.
  • Drug Development: Its unique trifluoromethyl group enhances the biological activity of drug candidates, making it valuable in the design of more effective medications.
  • Biochemical Research: Researchers use this compound to study protein interactions and enzyme activities, providing insights into metabolic pathways and disease mechanisms.
  • Material Science: The chemical's properties allow it to be incorporated into polymers, leading to materials with enhanced thermal stability and chemical resistance.
  • Fluorine Chemistry: Its trifluoromethyl group is beneficial in developing new fluorinated compounds, which are important in various applications, including agrochemicals and imaging agents.

Citations