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Catalog Number:
14496
CAS Number:
141743-14-8
Fmoc- N -(isobutyl)glycine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc- N -(isobutyle)-Gly-OH, Fmoc-Nleu-OH
Documents
$82.02 /100 mg
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Product Information

Fmoc-N-(isobutyl)glycine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique isobutyl side chain enhances the hydrophobic character of peptides, making it particularly valuable in the design of bioactive compounds and pharmaceuticals. Researchers appreciate its stability under various reaction conditions, allowing for efficient coupling reactions and facilitating the production of complex peptide sequences.

In practical applications, Fmoc-N-(isobutyl)glycine is often employed in the development of peptide-based therapeutics, including those targeting cancer and metabolic disorders. Its ability to improve solubility and bioavailability of peptides makes it a preferred choice among chemists and pharmaceutical developers. Additionally, the compound's compatibility with solid-phase peptide synthesis (SPPS) techniques streamlines the production process, ultimately leading to more efficient drug discovery and development workflows.

Synonyms
Fmoc- N -(isobutyle)-Gly-OH, Fmoc-Nleu-OH
CAS Number
141743-14-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C 21 H 234
Molecular Weight
353.42
MDL Number
MFCD18351999
PubChem ID
11727923
Melting Point
83 - 87 °C
Appearance
Solide blanc
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc- N -(isobutyle)-Gly-OH, Fmoc-Nleu-OH
CAS Number
141743-14-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C 21 H 234
Molecular Weight
353.42
MDL Number
MFCD18351999
PubChem ID
11727923
Melting Point
83 - 87 °C
Appearance
Solide blanc
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-N-(isobutyl)glycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It is used in the design of peptide-based therapeutics, enhancing the stability and bioavailability of drug candidates in pharmaceutical research.
  • Bioconjugation: The compound facilitates the attachment of peptides to various biomolecules, which is crucial in developing targeted drug delivery systems and diagnostic tools.
  • Research in Neuroscience: Its derivatives are explored in studies related to neurotransmitter modulation, contributing to the understanding of neurological disorders.
  • Material Science: Fmoc-N-(isobutyl)glycine is applied in creating functionalized surfaces and materials, which can be used in biosensors and other advanced materials.

Citations