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Catalog Number:
28570
CAS Number:
367927-39-7
6-(3-maléimidopropionamido)hexanoate de N -succinimidyle
Purity:
≥ 99 % (HPLC)
Synonym(s):
SMPH
Documents
$154.93 /25 mg
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Product Information

N-Succinimidyl 6-(3-maleimidopropionamido) hexanoate is a versatile chemical compound widely utilized in bioconjugation and protein labeling applications. This compound features a maleimide group, which is known for its ability to selectively react with thiol groups in proteins, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its unique structure allows for the formation of stable thioether bonds, facilitating the development of targeted drug delivery systems and diagnostic agents.

Researchers can leverage N-Succinimidyl 6-(3-maleimidopropionamido) hexanoate to create conjugates that enhance the specificity and efficacy of therapeutic agents. Its applications extend to the development of antibody-drug conjugates (ADCs), where it plays a crucial role in linking cytotoxic drugs to antibodies, thereby improving the targeting of cancer cells while minimizing side effects. Additionally, this compound is valuable in the creation of fluorescent probes for imaging studies, enabling scientists to visualize biological processes in real-time. With its robust reactivity and stability, N-Succinimidyl 6-(3-maleimidopropionamido) hexanoate stands out as a preferred choice for professionals seeking reliable solutions in protein engineering and drug development.

Synonyms
SMPH
CAS Number
367927-39-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C17H21N3O7
Molecular Weight
379.37
MDL Number
MFCD01863460
PubChem ID
4170355
Melting Point
114-127 ºC
Appearance
Poudre blanche
Conditions
Conserver à 0-8°C
General Information
Synonyms
SMPH
CAS Number
367927-39-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C17H21N3O7
Molecular Weight
379.37
MDL Number
MFCD01863460
PubChem ID
4170355
Melting Point
114-127 ºC
Appearance
Poudre blanche
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

N-Succinimidyl 6-(3-maleimidopropionamido) hexanoate is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker in bioconjugation processes, allowing researchers to attach biomolecules such as proteins or antibodies to surfaces or other molecules, enhancing drug delivery systems.
  • Diagnostic Applications: It is used in the development of diagnostic assays, particularly in creating labeled antibodies for detecting specific antigens, which is crucial in medical diagnostics and research.
  • Protein Engineering: The compound facilitates the modification of proteins, enabling scientists to create novel protein structures with tailored functionalities for therapeutic applications.
  • Vaccine Development: In vaccine research, it aids in the conjugation of antigens to carrier proteins, improving immune response and efficacy of vaccines.
  • Targeted Drug Delivery: This chemical plays a role in designing targeted drug delivery systems, allowing for precise delivery of therapeutics to specific cells or tissues, minimizing side effects and enhancing treatment outcomes.

Citations