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Catalog Number:
29746
CAS Number:
137234-62-9
Voriconazole
Purity:
97,5 - 102,0 % (HPLC, base sèche)
Synonym(s):
2R,3S-2-(2,4-difluorophényl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Hazmat
Antibiotic
Documents
$68.90 /250 mg
Taille
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Product Information

Voriconazole is a potent antifungal agent widely recognized for its effectiveness against a variety of fungal infections, particularly those caused by Aspergillus species and Candida. This compound is particularly valuable in clinical settings, where it is used to treat serious infections in immunocompromised patients. Voriconazole's unique mechanism of action involves inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, which leads to cell death. Its high bioavailability and ability to penetrate tissues make it an ideal choice for treating invasive fungal infections, especially in patients with compromised immune systems.

In addition to its therapeutic applications, Voriconazole has been extensively studied in research settings, contributing to the understanding of antifungal resistance mechanisms and the development of new antifungal therapies. Its favorable pharmacokinetic properties, including oral and intravenous formulations, enhance its versatility in treatment regimens. With ongoing research into its efficacy and safety, Voriconazole continues to be a cornerstone in antifungal therapy, providing significant benefits in both clinical and research environments.

Synonyms
2R,3S-2-(2,4-difluorophényl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
CAS Number
137234-62-9
Purity
97,5 - 102,0 % (HPLC, base sèche)
Molecular Formula
C 16 H 14 F 3 N 5 O
Molecular Weight
349.31
MDL Number
MFCD00905717
PubChem ID
5231054
Appearance
Poudre cristalline blanche à presque blanche
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
2R,3S-2-(2,4-difluorophényl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
CAS Number
137234-62-9
Purity
97,5 - 102,0 % (HPLC, base sèche)
Molecular Formula
C 16 H 14 F 3 N 5 O
Molecular Weight
349.31
MDL Number
MFCD00905717
PubChem ID
5231054
Appearance
Poudre cristalline blanche à presque blanche
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Oui
Antibiotic
Oui
DEA-regulated
Non
Warnings
-
Applications

Voriconazole is widely utilized in research focused on:

  • Antifungal Treatment: It is primarily used in the medical field for treating serious fungal infections, particularly in immunocompromised patients. This includes infections caused by Aspergillus and Candida species.
  • Pharmaceutical Development: Researchers use Voriconazole as a benchmark in the development of new antifungal agents, allowing for the comparison of efficacy and safety profiles in clinical trials.
  • In vitro Studies: It serves as a critical tool in laboratory settings to study fungal resistance mechanisms, helping scientists understand how certain fungi adapt to treatments.
  • Combination Therapy Research: Voriconazole is often tested in combination with other antifungal drugs to enhance therapeutic outcomes and reduce resistance, making it valuable in developing more effective treatment regimens.
  • Pharmacokinetic Studies: It is used to investigate how the body absorbs, distributes, metabolizes, and excretes antifungal medications, providing insights that can improve dosing strategies.

Citations