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Catalog Number:
37339
CAS Number:
7449-74-3
N-méthyl-N-triméthylsilylacétamide
Purity:
≥ 98% (CG)
Synonym(s):
N-Triméthylsilyl-N-méthylacétamide, MSA
Hazmat
Temperature Sensitive
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Product Information

N-Methyl-N-trimethylsilylacetamide is a versatile chemical compound widely utilized in various fields, particularly in organic synthesis and analytical chemistry. This compound serves as an effective silylating agent, enhancing the stability and volatility of sensitive compounds during gas chromatography and mass spectrometry analyses. Its unique structure allows for the protection of functional groups, making it invaluable in the synthesis of complex organic molecules. Researchers often leverage its properties to improve reaction yields and simplify purification processes, thereby streamlining workflows in both academic and industrial laboratories.

Additionally, N-Methyl-N-trimethylsilylacetamide is recognized for its role in the preparation of derivatives for various analytical techniques. Its ability to form stable derivatives with alcohols, amines, and carboxylic acids allows for improved detection and quantification of these compounds. This makes it particularly beneficial for applications in pharmaceuticals, environmental testing, and food safety analysis. By incorporating this compound into their methodologies, professionals can achieve enhanced sensitivity and specificity in their analytical results.

Synonyms
N-Triméthylsilyl-N-méthylacétamide, MSA
CAS Number
7449-74-3
Purity
≥ 98% (CG)
Molecular Formula
C6H15NOSi
Molecular Weight
145.28
MDL Number
MFCD00040758
PubChem ID
81953
Density
0,904 (lit.)
Appearance
Liquide clair
Boiling Point
154 - 161 °C (lit.)
Refractive Index
n20/D 1.439 (Lit.)
Conditions
Conserver à - 10 °C
General Information
Synonyms
N-Triméthylsilyl-N-méthylacétamide, MSA
CAS Number
7449-74-3
Purity
≥ 98% (CG)
Molecular Formula
C6H15NOSi
Molecular Weight
145.28
MDL Number
MFCD00040758
PubChem ID
81953
Density
0,904 (lit.)
Appearance
Liquide clair
Boiling Point
154 - 161 °C (lit.)
Refractive Index
n20/D 1.439 (Lit.)
Conditions
Conserver à - 10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Oui
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

N-Methyl-N-trimethylsilylacetamide is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, particularly in the synthesis of various functionalized compounds, enhancing reaction efficiency and selectivity.
  • Analytical Chemistry: It is commonly used as a derivatizing agent in gas chromatography (GC) to improve the volatility and detectability of polar compounds, making it easier for researchers to analyze complex mixtures.
  • Pharmaceutical Development: In drug formulation, it aids in the stabilization of active pharmaceutical ingredients (APIs), improving their solubility and bioavailability, which is crucial for effective medication.
  • Material Science: This chemical is applied in the development of silicone-based materials, providing enhanced thermal stability and mechanical properties, which are essential for high-performance applications.
  • Environmental Analysis: It plays a role in the extraction and analysis of environmental pollutants, allowing for more accurate assessments of contamination levels in soil and water samples.

Citations