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Catalog Number:
37807
CAS Number:
88416-50-6
Clodronate disodique tétrahydraté
Purity:
≥ 97% (RMN)
Synonym(s):
Acide clodronique sel disodique tétrahydraté, Acide dichlorométhylènediphosphonique sel disodique tétrahydraté
Documents
$111.17 /1G
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Product Information

Clodronate disodium tetrahydrate is a highly effective bisphosphonate compound primarily utilized in the treatment of bone-related disorders. This compound is particularly recognized for its ability to inhibit bone resorption, making it invaluable in managing conditions such as osteoporosis and Paget's disease. Its unique mechanism of action involves the selective targeting of osteoclasts, the cells responsible for bone breakdown, thereby promoting bone density and strength. Researchers and healthcare professionals appreciate Clodronate disodium tetrahydrate for its efficacy in reducing skeletal-related events in patients with metastatic bone disease, providing significant relief and improving quality of life.

In addition to its therapeutic applications, Clodronate disodium tetrahydrate is also employed in various research settings, particularly in studies focused on bone metabolism and the effects of bisphosphonates on cellular processes. Its stability and solubility in aqueous solutions make it suitable for both in vitro and in vivo studies. The compound's ability to modulate mineralization processes further enhances its relevance in the field of biomaterials and regenerative medicine, where it can be used to develop innovative treatments for bone repair and regeneration.

Synonyms
Acide clodronique sel disodique tétrahydraté, Acide dichlorométhylènediphosphonique sel disodique tétrahydraté
CAS Number
88416-50-6
Purity
≥ 97% (RMN)
Molecular Formula
CH 2 Cl 2 Na 2 O 6 P 2 ·4H 2 O
Molecular Weight
360.91
MDL Number
MFCD02940846
PubChem ID
23724874
Melting Point
211 - 214 °C
Appearance
Solide blanc
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Acide clodronique sel disodique tétrahydraté, Acide dichlorométhylènediphosphonique sel disodique tétrahydraté
CAS Number
88416-50-6
Purity
≥ 97% (RMN)
Molecular Formula
CH 2 Cl 2 Na 2 O 6 P 2 ·4H 2 O
Molecular Weight
360.91
MDL Number
MFCD02940846
PubChem ID
23724874
Melting Point
211 - 214 °C
Appearance
Solide blanc
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Clodronate disodium tetrahydrate is widely utilized in research focused on:

  • Bone Health Research: It is primarily used to study bone metabolism and the effects of bisphosphonates on osteoporosis, aiding researchers in developing treatments for bone density loss.
  • Cancer Treatment Studies: This compound is often investigated for its potential to inhibit bone resorption in cancer patients, particularly those with metastatic bone disease, providing insights into better management strategies.
  • Pharmaceutical Development: Clodronate is a key ingredient in formulations aimed at reducing skeletal-related events in patients with bone metastases, helping pharmaceutical companies create effective therapies.
  • Animal Models: Researchers utilize this compound in animal studies to evaluate the effects of bisphosphonates on bone health, which is crucial for preclinical testing of new drugs.
  • Regenerative Medicine: It is being explored for its role in enhancing bone regeneration processes, offering potential applications in tissue engineering and regenerative therapies.

Citations