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Catalog Number:
37813
CAS Number:
69123-98-4
Fialuridine
Purity:
≥ 98 % (HPLC)
Synonym(s):
1-(2-désoxy-2-fluoro-bD-arabinofuranosyl)-5-iodouracile, 2'-Fluoro-5-iodoarauracile
Documents
$232.25 /10 mg
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Product Information

Fialuridine is a potent nucleoside analog that has garnered attention for its potential applications in antiviral therapies, particularly in the treatment of hepatitis B. This compound exhibits unique structural features, including a fluorine atom and a hydroxymethyl group, which enhance its efficacy against viral replication. Researchers have explored its use in combination therapies, demonstrating promising results in inhibiting viral load and improving patient outcomes. Fialuridine's ability to interfere with nucleic acid synthesis makes it a valuable tool in the development of antiviral agents, offering a targeted approach to combatting persistent viral infections.

In addition to its antiviral properties, Fialuridine is also being investigated for its potential in cancer research, where it may serve as a chemotherapeutic agent due to its ability to disrupt cellular proliferation. Its unique mechanism of action sets it apart from other nucleoside analogs, making it a subject of interest for ongoing studies in both virology and oncology. With its multifaceted applications, Fialuridine represents a significant advancement in therapeutic strategies aimed at tackling viral diseases and cancer.

Synonyms
1-(2-désoxy-2-fluoro-bD-arabinofuranosyl)-5-iodouracile, 2'-Fluoro-5-iodoarauracile
CAS Number
69123-98-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C9H10FIN2O5
Molecular Weight
372.09
MDL Number
MFCD00866922
PubChem ID
386483
Melting Point
226 °C
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
1-(2-désoxy-2-fluoro-bD-arabinofuranosyl)-5-iodouracile, 2'-Fluoro-5-iodoarauracile
CAS Number
69123-98-4
Purity
≥ 98 % (HPLC)
Molecular Formula
C9H10FIN2O5
Molecular Weight
372.09
MDL Number
MFCD00866922
PubChem ID
386483
Melting Point
226 °C
Appearance
Poudre blanche à presque blanche à cristal
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fialuridine is widely utilized in research focused on:

  • Antiviral Research: It has been investigated as a potential treatment for hepatitis B, showcasing its ability to inhibit viral replication, which is crucial for developing effective therapies.
  • Pharmaceutical Development: This compound serves as a model for designing new nucleoside analogs, helping researchers create drugs with improved efficacy and reduced side effects.
  • Biochemical Studies: Fialuridine is used in studies to understand nucleic acid metabolism, providing insights into cellular processes and potential therapeutic targets.
  • Drug Resistance Research: It helps in exploring mechanisms of drug resistance in viral infections, aiding in the development of strategies to overcome resistance.
  • Clinical Trials: Fialuridine has been part of clinical trials, allowing researchers to assess its safety and effectiveness in human subjects, which is essential for advancing medical treatments.

Citations