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Catalog Number:
43814
CAS Number:
170491-63-1
N- ( tert -butoxycarbonyl)-DL-prolinol
Purity:
≥ 98% (CG)
Synonym(s):
N -Boc-DL-prolinol, 1-( tert -butoxycarbonyl)-2-pyrrolidineméthanol, 1-Boc-2-pyrrolidineméthanol
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Product Information

N-(tert-Butoxycarbonyl)-DL-prolinol is a versatile compound widely utilized in the fields of organic synthesis and pharmaceutical development. This compound, also known as tert-butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate, serves as an important building block in the synthesis of various bioactive molecules. Its unique structure allows for the introduction of functional groups, making it an ideal candidate for the development of peptide-based therapeutics and other complex organic compounds. Researchers appreciate its stability and ease of handling, which facilitate its application in diverse synthetic pathways.

In addition to its role in organic synthesis, N-(tert-Butoxycarbonyl)-DL-prolinol is particularly valuable in the production of chiral intermediates, which are crucial for the development of enantiomerically pure pharmaceuticals. Its ability to act as a protecting group for amines further enhances its utility in multi-step synthesis processes. With its favorable properties and broad applicability, this compound stands out as a key reagent for chemists and researchers aiming to innovate in drug discovery and development.

Synonyms
N -Boc-DL-prolinol, 1-( tert -butoxycarbonyl)-2-pyrrolidineméthanol, 1-Boc-2-pyrrolidineméthanol
CAS Number
170491-63-1
Purity
≥ 98% (CG)
Molecular Formula
C 10 H 19 NON 3
Molecular Weight
201.27
MDL Number
MFCD01456556
PubChem ID
550865
Melting Point
52 - 56 °C
Appearance
Poudre cristalline blanche à presque blanche
Conditions
Magasin chez RT
General Information
Synonyms
N -Boc-DL-prolinol, 1-( tert -butoxycarbonyl)-2-pyrrolidineméthanol, 1-Boc-2-pyrrolidineméthanol
CAS Number
170491-63-1
Purity
≥ 98% (CG)
Molecular Formula
C 10 H 19 NON 3
Molecular Weight
201.27
MDL Number
MFCD01456556
PubChem ID
550865
Melting Point
52 - 56 °C
Appearance
Poudre cristalline blanche à presque blanche
Conditions
Magasin chez RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

N-(tert-Butoxycarbonyl)-DL-prolinol is widely utilized in research focused on:

  • Synthesis of Peptides: This compound serves as a protecting group for amino acids during peptide synthesis, enhancing the efficiency and selectivity of reactions.
  • Pharmaceutical Development: It is used in the creation of novel drug candidates, particularly in the development of prodrugs that improve bioavailability and therapeutic efficacy.
  • Organic Synthesis: Researchers leverage its properties for constructing complex organic molecules, making it a valuable tool in synthetic organic chemistry.
  • Chiral Auxiliary: The compound acts as a chiral auxiliary in asymmetric synthesis, facilitating the production of enantiomerically pure compounds, which is crucial in drug development.
  • Bioconjugation: It is employed in bioconjugation techniques, allowing for the attachment of biomolecules to surfaces or other molecules, which is important in diagnostics and therapeutic applications.

Citations