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Catalog Number:
00060
CAS Number:
75621-03-3
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
Grade:
Molecular Biology Grade
Purity:
≥ 98% (HPLC)
Synonym(s):
CHAPS
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Product Information

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate, commonly known as CHAPS, is a zwitterionic detergent widely utilized in biochemical and molecular biology applications. Its unique structure allows it to solubilize membrane proteins while maintaining their functional integrity, making it an essential tool for researchers working with proteins and lipids. CHAPS is particularly effective in applications such as protein purification, enzyme assays, and the stabilization of membrane proteins for structural studies. Its mild nature compared to other detergents makes it suitable for sensitive biological systems, ensuring minimal disruption to protein structure and function.

In addition to its role in protein studies, CHAPS is also employed in the formulation of various cosmetic and pharmaceutical products due to its emulsifying properties. Its ability to enhance the solubility of hydrophobic compounds makes it valuable in drug delivery systems and formulations requiring improved bioavailability. Researchers and industry professionals appreciate CHAPS for its versatility, effectiveness, and compatibility with a wide range of biological systems, making it a preferred choice in both academic and industrial settings.

Synonyms
CHAPS
CAS Number
75621-03-3
Purity
≥ 98% (HPLC)
Grade
Molecular Biology Grade
Molecular Formula
C32H58N2O7S
Molecular Weight
614.9
MDL Number
MFCD00081083
PubChem ID
3659871
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
CHAPS
CAS Number
75621-03-3
Purity
≥ 98% (HPLC)
Grade
Molecular Biology Grade
Molecular Formula
C32H58N2O7S
Molecular Weight
614.9
MDL Number
MFCD00081083
PubChem ID
3659871
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate is widely utilized in research focused on:

  • Biotechnology: This compound serves as a critical component in membrane protein studies, helping to solubilize and stabilize proteins for analysis, which is essential in drug development and enzyme research.
  • Pharmaceuticals: It is used as a surfactant in drug formulations, enhancing the solubility and bioavailability of poorly soluble drugs, thus improving therapeutic outcomes.
  • Cell Biology: The chemical is applied in cell culture systems to facilitate the study of cellular processes, including membrane dynamics and protein interactions, providing insights into disease mechanisms.
  • Diagnostics: It plays a role in the preparation of samples for various diagnostic assays, ensuring accurate results in clinical laboratories by improving the extraction of biomolecules.
  • Cosmetics: This compound is incorporated into cosmetic formulations as an emulsifier, helping to create stable products that enhance skin absorption and overall effectiveness.

Citations