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Catalog Number:
00106
CAS Number:
951-78-0
2'-Deoxyuridine
Purity:
97 to 102% (UV, dry basis)
Synonym(s):
2'-dU, Uracil deoxyriboside, 1-(2-Deoxy-β-D-ribofuranosyl)uracil
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Product Information

2'-Deoxyuridine is a nucleoside analog that plays a crucial role in molecular biology and biochemistry. This compound is essential for DNA synthesis and repair, making it a valuable tool in various research applications, particularly in the fields of genetics and virology. Its unique structure allows it to be incorporated into DNA in place of uridine, which can be particularly useful in studying the mechanisms of DNA replication and repair. Researchers often utilize 2'-Deoxyuridine in the development of antiviral therapies and cancer treatments, as it can inhibit the replication of certain viruses and cancer cells.

In addition to its applications in research, 2'-Deoxyuridine is also used in the synthesis of modified nucleotides, which are important for the development of diagnostic tools and therapeutic agents. Its ability to act as a substrate for DNA polymerases makes it an excellent candidate for use in various assays and experiments aimed at understanding nucleic acid interactions. With its versatile applications and significant relevance in both academic and industrial settings, 2'-Deoxyuridine continues to be a compound of interest for researchers and professionals alike.

Synonyms
2'-dU, Uracil deoxyriboside, 1-(2-Deoxy-β-D-ribofuranosyl)uracil
CAS Number
951-78-0
Purity
97 to 102% (UV, dry basis)
Molecular Formula
C9H12N2O5
Molecular Weight
228.2
MDL Number
MFCD00006527
PubChem ID
640
Melting Point
163-168 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D25 = +28.8° to 30.8° (C=2 in H2O)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
2'-dU, Uracil deoxyriboside, 1-(2-Deoxy-β-D-ribofuranosyl)uracil
CAS Number
951-78-0
Purity
97 to 102% (UV, dry basis)
Molecular Formula
C9H12N2O5
Molecular Weight
228.2
MDL Number
MFCD00006527
PubChem ID
640
Melting Point
163-168 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D25 = +28.8° to 30.8° (C=2 in H2O)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2'-Deoxyuridine is widely utilized in research focused on:

  • DNA Synthesis: It serves as a building block for synthesizing DNA, making it crucial in molecular biology and genetic engineering applications.
  • Antiviral Research: This compound is studied for its potential in developing antiviral drugs, particularly against viruses like HIV and herpes simplex virus, providing a pathway for innovative treatments.
  • Cellular Studies: Researchers use it to investigate cellular processes and mechanisms, especially in studies related to cell proliferation and differentiation.
  • Pharmaceutical Development: It plays a role in formulating nucleoside analogs, which are important in cancer therapy, offering targeted treatment options with fewer side effects.
  • Genetic Studies: The compound is essential in studying mutations and genetic disorders, helping to advance our understanding of hereditary diseases and potential therapies.

Citations