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Catalog Number:
00132
CAS Number:
64325-78-6
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine
Purity:
≥ 99% (HPLC)
Synonym(s):
5'-O-DMT-NBz-2'-dA
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine is a versatile nucleoside derivative widely utilized in the fields of molecular biology and biochemistry. This compound serves as a crucial building block in the synthesis of oligonucleotides, enabling researchers to create custom DNA sequences for various applications, including gene therapy, diagnostics, and synthetic biology. Its unique structure, featuring both a protective dimethoxytrityl group and a benzoyl moiety, enhances stability and solubility, making it an ideal choice for sensitive reactions and prolonged storage.

In addition to its role in oligonucleotide synthesis, this compound is also valuable in the development of nucleotide analogs and as a substrate in enzymatic reactions. Its ability to facilitate the incorporation of modified nucleotides into DNA strands allows for the exploration of novel therapeutic strategies and the study of gene function. With its reliable performance and compatibility with various synthetic methodologies, 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine is an essential tool for researchers aiming to advance genetic research and biotechnological innovations.

Synonyms
5'-O-DMT-NBz-2'-dA
CAS Number
64325-78-6
Purity
≥ 99% (HPLC)
Molecular Formula
C38H35N5O6
Molecular Weight
657.74
MDL Number
MFCD00010058
PubChem ID
3709159
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
5'-O-DMT-NBz-2'-dA
CAS Number
64325-78-6
Purity
≥ 99% (HPLC)
Molecular Formula
C38H35N5O6
Molecular Weight
657.74
MDL Number
MFCD00010058
PubChem ID
3709159
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, essential for genetic research and therapeutic applications.
  • Gene Therapy: It plays a crucial role in developing gene therapies, where modified nucleotides are used to deliver genetic material into cells effectively.
  • Diagnostics: The chemical is used in the production of probes for molecular diagnostics, aiding in the detection of specific DNA or RNA sequences in clinical samples.
  • Pharmaceutical Development: It is involved in the formulation of antiviral and anticancer drugs, enhancing their efficacy by improving stability and bioavailability.
  • Research in Molecular Biology: This compound is utilized in various molecular biology techniques, such as PCR and sequencing, facilitating advancements in genomics and proteomics.

Citations