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Catalog Number:
00142
CAS Number:
128-53-0
N-Ethylmaleimide
Purity:
≥ 99% (GC)
Synonym(s):
NEM, 1-Ethyl-1H-pyrrole-2,5-dione
Hazmat
Documents
$18.53 /1G
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Product Information

N-Ethylmaleimide is a versatile compound widely recognized for its applications in organic synthesis and polymer chemistry. This cyclic imide is particularly valued for its ability to act as a reactive intermediate in the formation of various polymers and copolymers, making it essential in the production of specialty materials. Its unique reactivity allows it to participate in Michael addition reactions, which are crucial in the development of high-performance adhesives, coatings, and sealants. Additionally, N-Ethylmaleimide serves as a valuable reagent in bioconjugation processes, enabling the modification of biomolecules for drug delivery systems and diagnostic applications.

Researchers and industry professionals appreciate N-Ethylmaleimide for its stability and ease of handling, which contribute to its effectiveness in diverse formulations. Its ability to enhance the properties of polymers, such as thermal stability and mechanical strength, positions it as a key ingredient in advanced material science. With its broad range of applications and benefits, N-Ethylmaleimide continues to be a compound of choice for innovative solutions in various fields.

Synonyms
NEM, 1-Ethyl-1H-pyrrole-2,5-dione
CAS Number
128-53-0
Purity
≥ 99% (GC)
Molecular Formula
C6H7NO2
Molecular Weight
125.13
MDL Number
MFCD00005509
PubChem ID
4362
Melting Point
42 - 47 °C
Appearance
White to pale yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
NEM, 1-Ethyl-1H-pyrrole-2,5-dione
CAS Number
128-53-0
Purity
≥ 99% (GC)
Molecular Formula
C6H7NO2
Molecular Weight
125.13
MDL Number
MFCD00005509
PubChem ID
4362
Melting Point
42 - 47 °C
Appearance
White to pale yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Ethylmaleimide is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a reactive agent for attaching biomolecules, such as proteins and peptides, to surfaces or other molecules, enhancing drug delivery systems and diagnostic tools.
  • Polymer Chemistry: It is used in the synthesis of various polymers, particularly in creating thermosetting resins, which are valued for their durability and heat resistance in industrial applications.
  • Pharmaceutical Development: N-Ethylmaleimide plays a role in drug formulation, particularly in stabilizing active ingredients and improving the solubility of poorly soluble drugs.
  • Protein Modification: Researchers utilize it to selectively modify cysteine residues in proteins, aiding in the study of protein function and interactions, which is crucial for understanding diseases.
  • Diagnostics: Its reactivity allows for the development of sensitive assays for detecting biomolecules, making it valuable in clinical diagnostics and research laboratories.

Citations