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Catalog Number:
00306
CAS Number:
50-89-5
Thymidine
Purity:
≥ 99% (HPLC)
Synonym(s):
2'-Deoxythymidine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, dT
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$20.20 /5G
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Product Information

Thymidine is a nucleoside that plays a crucial role in the synthesis of DNA, making it an essential compound in molecular biology and biochemistry. It is recognized for its application in various fields, including genetic research, virology, and cancer studies. Thymidine is often utilized in the production of nucleic acid probes and as a substrate in DNA polymerase reactions, facilitating the study of DNA replication and repair mechanisms. Its unique structure allows it to be incorporated into DNA strands, which is vital for understanding genetic mutations and developing therapeutic strategies against viral infections and tumors.

In addition to its research applications, Thymidine is also employed in the pharmaceutical industry for the synthesis of antiviral and anticancer agents. Its ability to mimic natural nucleosides makes it a valuable tool for drug development, particularly in designing treatments that target rapidly dividing cells. Researchers and industry professionals appreciate Thymidine for its reliability and effectiveness in various experimental protocols, making it a staple in laboratories focused on genetic and cellular studies.

Synonyms
2'-Deoxythymidine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, dT
CAS Number
50-89-5
Purity
≥ 99% (HPLC)
Molecular Formula
C10H14N2O5
Molecular Weight
242.23
MDL Number
MFCD00006537
PubChem ID
1134
Melting Point
185 - 190 °C
Appearance
White to off-white powder or crystalline
Optical Rotation
[a]D20 = 18 - 34 °
Conditions
Store at RT
General Information
Synonyms
2'-Deoxythymidine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil, dT
CAS Number
50-89-5
Purity
≥ 99% (HPLC)
Molecular Formula
C10H14N2O5
Molecular Weight
242.23
MDL Number
MFCD00006537
PubChem ID
1134
Melting Point
185 - 190 °C
Appearance
White to off-white powder or crystalline
Optical Rotation
[a]D20 = 18 - 34 °
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Thymidine is widely utilized in research focused on:

  • DNA Synthesis: Thymidine is a key building block in the synthesis of DNA, making it essential for molecular biology studies, including cloning and gene expression analysis.
  • Cell Culture: In cell culture applications, thymidine is used to promote cell proliferation and is often included in media to support the growth of various cell lines.
  • Antiviral Research: Thymidine is studied for its potential in antiviral therapies, particularly in the development of treatments for viral infections like herpes simplex virus.
  • Radiation Protection: It has applications in radiobiology, where thymidine is used to study the effects of radiation on DNA and to explore protective measures against radiation damage.
  • Diagnostic Tools: Thymidine is employed in diagnostic assays, such as measuring cell proliferation in cancer research, helping to identify tumor growth and response to therapies.

Citations