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Catalog Number:
00664
CAS Number:
316-46-1
5-Fluorouridine
Purity:
≥ 99% (HPLC)
Synonym(s):
2,4-Dihydroxy-5-Fluoro-1-β-D-ribofuranosylpyrimidine, 5-Fluoro-1-(β-D-ribofuranosyl)uracil
Documents
$22.03 /1G
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Product Information

5-Fluorouridine is a fluorinated nucleoside analog that plays a significant role in pharmaceutical and biochemical research. This compound is particularly valued for its application in the development of antiviral and anticancer therapies. Its structural similarity to uridine allows it to interfere with RNA synthesis, making it a potent candidate for targeting viral infections and certain types of cancer. Researchers have utilized 5-Fluorouridine in various studies to explore its efficacy against RNA viruses, including those responsible for hepatitis and influenza, as well as its potential in enhancing the effectiveness of existing chemotherapeutic agents.

The unique properties of 5-Fluorouridine, such as its ability to inhibit RNA polymerase, provide a strategic advantage in drug formulation. Its incorporation into RNA can lead to the production of faulty proteins, thereby disrupting viral replication and tumor growth. This compound is also being investigated for its synergistic effects when combined with other nucleoside analogs, which may enhance therapeutic outcomes. With its promising applications in both research and clinical settings, 5-Fluorouridine stands out as a valuable tool for scientists and healthcare professionals aiming to combat viral diseases and cancer.

Synonyms
2,4-Dihydroxy-5-Fluoro-1-β-D-ribofuranosylpyrimidine, 5-Fluoro-1-(β-D-ribofuranosyl)uracil
CAS Number
316-46-1
Purity
≥ 99% (HPLC)
Molecular Formula
C9H11FN2O6
Molecular Weight
262.2
MDL Number
MFCD00036832
PubChem ID
1821
Melting Point
173-184 ºC
Appearance
White or off-white powder
Optical Rotation
[α]D20 = +15.0 to 20.0º (C=1 in H2O)
Conditions
Store at 0-8 °C
General Information
Synonyms
2,4-Dihydroxy-5-Fluoro-1-β-D-ribofuranosylpyrimidine, 5-Fluoro-1-(β-D-ribofuranosyl)uracil
CAS Number
316-46-1
Purity
≥ 99% (HPLC)
Molecular Formula
C9H11FN2O6
Molecular Weight
262.2
MDL Number
MFCD00036832
PubChem ID
1821
Melting Point
173-184 ºC
Appearance
White or off-white powder
Optical Rotation
[α]D20 = +15.0 to 20.0º (C=1 in H2O)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluorouridine is widely utilized in research focused on:

  • Antiviral Research: It serves as a crucial compound in developing antiviral therapies, particularly against RNA viruses. Its ability to inhibit viral replication makes it a valuable tool in drug discovery.
  • Cancer Treatment: This compound is investigated for its potential in cancer therapies, especially in combination with other chemotherapeutic agents. It can enhance the efficacy of treatments by targeting cancer cell metabolism.
  • RNA Studies: Researchers use it to study RNA metabolism and function. Its incorporation into RNA allows scientists to explore RNA processing and the effects of fluorinated nucleotides.
  • Pharmaceutical Development: It plays a role in the formulation of new drugs, particularly in the design of nucleoside analogs that can improve therapeutic outcomes in various diseases.
  • Diagnostic Tools: The compound is also being explored for use in diagnostic applications, where its unique properties can aid in the detection of specific viral infections or cancer markers.

Citations