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Catalog Number:
00714
CAS Number:
605-65-2
Dansyl chloride
Purity:
≥ 98% (HPLC)
Synonym(s):
5-(Dimethylamino)naphthalene-1-sulfonyl chloride
Hazmat
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Product Information

Dansyl chloride is a versatile chemical compound widely utilized in biochemical research and analytical chemistry. Known for its fluorescent properties, this sulfonyl chloride derivative is particularly valuable in labeling amino acids, peptides, and proteins, enabling researchers to track and visualize these biomolecules in various applications. Its ability to form stable conjugates with amines makes it an essential tool in the synthesis of fluorescent probes, which are crucial for studying cellular processes and interactions.

In addition to its applications in fluorescence microscopy and flow cytometry, Dansyl chloride is also employed in the development of biosensors and drug delivery systems. Its unique properties allow for the selective tagging of biomolecules, enhancing the sensitivity and specificity of assays. Researchers appreciate Dansyl chloride for its ease of use and effectiveness in providing clear, quantifiable results, making it a preferred choice for those in the fields of biochemistry and molecular biology.

Synonyms
5-(Dimethylamino)naphthalene-1-sulfonyl chloride
CAS Number
605-65-2
Purity
≥ 98% (HPLC)
Molecular Formula
C12H12ClNO2S
Molecular Weight
269.74
PubChem ID
11801
Melting Point
68 - 73 °C
Appearance
Light yellow or brown crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-(Dimethylamino)naphthalene-1-sulfonyl chloride
CAS Number
605-65-2
Purity
≥ 98% (HPLC)
Molecular Formula
C12H12ClNO2S
Molecular Weight
269.74
PubChem ID
11801
Melting Point
68 - 73 °C
Appearance
Light yellow or brown crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dansyl chloride is widely utilized in research focused on:

  • Fluorescent Labeling: It is commonly used to label proteins and peptides, allowing researchers to track biological processes through fluorescence microscopy.
  • Biochemical Assays: Dansyl chloride serves as a reagent in various biochemical assays, helping to determine the presence of amino acids and other biomolecules in samples.
  • Drug Development: In pharmaceutical research, it aids in the study of drug interactions with proteins, enhancing the understanding of drug mechanisms and efficacy.
  • Environmental Analysis: This compound is utilized in environmental chemistry to detect and quantify pollutants, contributing to cleaner and safer ecosystems.
  • Cell Biology: It plays a significant role in cell biology studies, particularly in understanding cellular uptake and localization of molecules, which is crucial for developing targeted therapies.

Citations