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Catalog Number:
00799
CAS Number:
49757-42-8
4,4',4"-Trimethoxytrityl chloride
Purity:
≥ 99% (HPLC)
Synonym(s):
4,4',4''-Trimethoxytriphenylmethyl chloride
Documents
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Product Information

4,4',4"-Trimethoxytrityl chloride is a versatile reagent widely utilized in organic synthesis, particularly in the field of nucleic acid chemistry. This compound serves as a protective group for hydroxyl functionalities, enabling the selective modification of nucleotides and oligonucleotides. Its unique structure allows for efficient protection and subsequent deprotection, making it invaluable in the synthesis of complex biomolecules. Researchers appreciate its stability and ease of use, which streamline the synthesis process in both academic and industrial laboratories.

In addition to its role in nucleic acid synthesis, 4,4',4"-Trimethoxytrityl chloride is also employed in the development of pharmaceuticals and fine chemicals. Its ability to facilitate the formation of intricate molecular architectures makes it a preferred choice for chemists looking to enhance the efficiency of their synthetic routes. The compound's favorable reactivity profile and compatibility with various reaction conditions further solidify its position as a key player in modern organic synthesis.

Synonyms
4,4',4''-Trimethoxytriphenylmethyl chloride
CAS Number
49757-42-8
Purity
≥ 99% (HPLC)
Molecular Formula
C22H21ClO3
Molecular Weight
368.86
MDL Number
MFCD00008408
PubChem ID
630505
Melting Point
148 - 157 ºC
Appearance
Off-white to orange
Conditions
Store at 0 - 8 °C
General Information
Synonyms
4,4',4''-Trimethoxytriphenylmethyl chloride
CAS Number
49757-42-8
Purity
≥ 99% (HPLC)
Molecular Formula
C22H21ClO3
Molecular Weight
368.86
MDL Number
MFCD00008408
PubChem ID
630505
Melting Point
148 - 157 ºC
Appearance
Off-white to orange
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4,4',4"-Trimethoxytrityl chloride is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a protecting group in the synthesis of oligonucleotides, enhancing the efficiency and yield of DNA and RNA production.
  • Pharmaceutical Development: It plays a crucial role in the development of new drugs by facilitating the modification of nucleosides and nucleotides, which are vital for therapeutic agents.
  • Biotechnology: The compound is used in various biotechnological applications, including gene therapy, where it aids in the stabilization of genetic materials.
  • Analytical Chemistry: It acts as a reagent in analytical methods, improving the detection and quantification of specific biomolecules in complex mixtures.
  • Research Laboratories: Commonly found in academic and industrial labs, it is essential for researchers working on chemical modifications and synthesis of complex organic molecules.

Citations