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Catalog Number:
00816
CAS Number:
1400-61-9
Nystatin
Grade:
USP
Synonym(s):
Mycostatin, Fungicidin
Antibiotic
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Product Information

Nystatin is a polyene antifungal antibiotic that is primarily used in the treatment of fungal infections, particularly those caused by Candida species. This compound is notable for its ability to bind to sterols in fungal cell membranes, leading to increased permeability and ultimately cell death. Nystatin is widely utilized in both clinical and laboratory settings, making it an essential tool for researchers and healthcare professionals. Its applications extend to topical formulations for skin infections, oral suspensions for gastrointestinal candidiasis, and even in veterinary medicine for treating fungal infections in animals.

In addition to its antifungal properties, Nystatin is also being explored for its potential in combination therapies, enhancing the efficacy of other antifungal agents. Its unique mechanism of action offers a significant advantage over other antifungal compounds, particularly in cases of resistant fungal strains. Researchers appreciate Nystatin for its reliability and effectiveness, making it a preferred choice in both pharmaceutical formulations and experimental studies. With its proven track record and versatility, Nystatin remains a critical component in the fight against fungal infections.

Synonyms
Mycostatin, Fungicidin
CAS Number
1400-61-9
Grade
USP
Molecular Formula
C47H75NO17
Molecular Weight
926.1
MDL Number
MFCD27989284
PubChem ID
6433272
Melting Point
> 160 °C (Decomposes without melting)
Appearance
Yellowish to light tan powder
Conditions
Store at ≤ -4 °C
Potency
≥ 4400 u/mg
General Information
Synonyms
Mycostatin, Fungicidin
CAS Number
1400-61-9
Grade
USP
Molecular Formula
C47H75NO17
Molecular Weight
926.1
MDL Number
MFCD27989284
PubChem ID
6433272
Melting Point
> 160 °C (Decomposes without melting)
Appearance
Yellowish to light tan powder
Conditions
Store at ≤ -4 °C
Potency
≥ 4400 u/mg
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Nystatin is widely utilized in research focused on:

  • Antifungal Treatments: Commonly used in the medical field to treat fungal infections, particularly those caused by Candida species. It is effective for patients with weakened immune systems.
  • Pharmaceutical Formulations: Incorporated into topical creams, ointments, and oral suspensions, providing a versatile option for treating localized infections.
  • Veterinary Medicine: Employed in veterinary practices to manage fungal infections in animals, ensuring the health and well-being of pets and livestock.
  • Research Applications: Used in laboratory settings to study fungal biology and resistance mechanisms, aiding in the development of new antifungal agents.
  • Food Preservation: Investigated for its potential use as a natural preservative in food products, helping to inhibit fungal growth and extend shelf life.

Citations