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Catalog Number:
00873
CAS Number:
85326-06-3
2',3'-Dideoxyguanosine
Purity:
≥ 99% (HPLC)
Synonym(s):
ddG
Documents
$100.05 /100MG
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Product Information

2',3'-Dideoxyguanosine is a crucial nucleoside analog that plays a significant role in antiviral and anticancer research. This compound is particularly valuable in the development of therapies targeting viral infections such as HIV, where it acts as a reverse transcriptase inhibitor, effectively halting viral replication. Its unique structure, which lacks the 2'-hydroxyl group found in natural nucleosides, enhances its ability to interfere with nucleic acid synthesis, making it a potent tool in molecular biology and pharmacology.

In addition to its antiviral applications, 2',3'-Dideoxyguanosine is also explored in cancer research, where it shows promise in inhibiting tumor cell proliferation. Researchers appreciate its specificity and efficacy, which can lead to fewer side effects compared to traditional chemotherapeutic agents. The compound's versatility in various biochemical assays further underscores its importance in both academic and industrial settings, providing a reliable option for those investigating nucleoside metabolism and drug development.

Synonyms
ddG
CAS Number
85326-06-3
Purity
≥ 99% (HPLC)
Molecular Formula
C10H13N5O3
Molecular Weight
251.2
MDL Number
MFCD00057074
PubChem ID
135406394
Appearance
White to off-white crystalline powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
ddG
CAS Number
85326-06-3
Purity
≥ 99% (HPLC)
Molecular Formula
C10H13N5O3
Molecular Weight
251.2
MDL Number
MFCD00057074
PubChem ID
135406394
Appearance
White to off-white crystalline powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2',3'-Dideoxyguanosine is widely utilized in research focused on:

  • Antiviral Drug Development: This compound is a key component in the synthesis of antiviral medications, particularly for treating HIV and hepatitis. Its ability to inhibit viral replication makes it invaluable in pharmaceutical research.
  • Gene Therapy: Researchers use it to create modified nucleotides for gene therapy applications, helping to develop treatments for genetic disorders by facilitating targeted gene editing.
  • Biochemical Research: It serves as a crucial tool in studying nucleic acid interactions and enzyme activities, allowing scientists to explore fundamental biological processes.
  • Diagnostic Tools: The compound is incorporated into diagnostic assays, aiding in the detection of viral infections and genetic mutations, which is essential for personalized medicine.
  • Comparative Studies: Its unique structure allows for comparative studies with other nucleosides, helping researchers understand the mechanisms of action and resistance in viral pathogens.

Citations