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Catalog Number:
01343
CAS Number:
21947-98-8
Boc-S-trityl-L-cysteine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-L-Cys(Trt)-OH, (R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionicacid
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Product Information

Boc-S-trityl-L-cysteine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to protect the thiol group of cysteine during chemical reactions, making it an essential building block in the design of peptides and proteins. Its unique trityl protecting group enhances stability and solubility, facilitating various applications in organic synthesis and medicinal chemistry. Researchers often utilize Boc-S-trityl-L-cysteine in the development of targeted therapeutics, where precise control over the structure of peptides is paramount.

In addition to its applications in peptide synthesis, Boc-S-trityl-L-cysteine is also explored for its potential in the development of novel pharmaceuticals, particularly in the fields of cancer research and drug delivery systems. Its ability to form stable conjugates with other biomolecules opens up avenues for innovative therapeutic strategies. With its favorable properties and broad applicability, Boc-S-trityl-L-cysteine stands out as a valuable compound for researchers and industry professionals seeking to advance their work in biochemistry and pharmaceutical development.

Synonyms
Boc-L-Cys(Trt)-OH, (R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionicacid
CAS Number
21947-98-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C27H29NO4S
Molecular Weight
463.57
MDL Number
MFCD00038251
PubChem ID
89557
Melting Point
142 - 150 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 28 ± 2 ° (C=1, in EtOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Cys(Trt)-OH, (R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionicacid
CAS Number
21947-98-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C27H29NO4S
Molecular Weight
463.57
MDL Number
MFCD00038251
PubChem ID
89557
Melting Point
142 - 150 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 28 ± 2 ° (C=1, in EtOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-S-trityl-L-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing researchers to selectively modify amino acids without affecting others. This is particularly useful in the development of complex therapeutic peptides.
  • Drug Development: Its unique structure aids in the design of novel drugs, especially in targeting specific biological pathways. The ability to manipulate its properties can lead to more effective treatments in pharmaceuticals.
  • Bioconjugation: The compound can be used to create bioconjugates, which are essential in developing targeted drug delivery systems. This application is crucial in cancer therapy, where precision is key.
  • Research in Protein Engineering: It plays a significant role in modifying proteins to study their functions and interactions. This is vital in fields like biotechnology and molecular biology.
  • Antioxidant Studies: Researchers explore its potential antioxidant properties, which can lead to advancements in health supplements and nutraceuticals aimed at reducing oxidative stress.

Citations